Computer for Ultrastructure Research and Molecular Biology

这组结构生物学的研究人员利用 传统的电子显微镜和计算机断层扫描， 与高压电子显微镜的联系。 的 这些项目的计算机组件依赖于 光栅图形、大磁盘空间和内存的可用性。 该补助金的资助设备包括DEC和SUN 提供高速运算的计算机硬件 能力。使用共享工具是适当的 因为大部分现有的内部开发的软件 写的目的是为了适应广泛的 应用程序，因为共享设施导致最 有效利用资源。 细胞及其亚结构成分的可视化 一直是并将继续是现代社会的重要目标之一。 生物学 电子显微镜提供了强大的放大能力 足以对细胞器和大分子复合物进行成像。 连续切片的复杂三维重建是 由计算机执行，提供这些复合物的图片。 结构将通过电子显微镜和高 电压电子显微镜包括核糖体，膜通道， 有丝分裂器的组成部分和纤毛。

This group of investigators in structural biology utilize the conventional electron microscope and computer tomography in association with the high-voltage electron microscope. The computer-based components of these projects rely on the availability of raster graphics, large disk space, and memory. The funded equipment of this grant consists of DEC and SUN computer hardware which will provide high speed computing capability. The use of shared instrumentation is appropriate because the bulk of existing software developed in-house has been written with a view towards accommodating a wide range of applications, and because a shared facility leads to the most efficient use of resources. Visualization of the cell and its substructural components has been and continues to be one of the important goals of modern biology. Electron microscopy provides magnification powerful enough to image cellular organelles and macromolecular complexes. The complex 3-dimensional reconstruction of serial sections is performed by computer, providing a picture of these complexes. Structures to be investigated by electron microscopy and high voltage electron microscopy include ribosomes, membrane channels, components of the mitotic apparatus, and cilia.