A Chemical Investigation of the Jordanian Flora

描述：该项目支持约旦大学的一名科学家(M.H.Abu Zarga博士)与宾夕法尼亚州立大学化学系的Maurice Shamma博士共同参与的一个研究项目，该项目旨在调查各种约旦植物的化学成分。这些植物将包括仙人掌、秋水仙草和银色拟甲藻。这位约旦科学家将在宾夕法尼亚州立大学呆上大约五个月，对这些植物的成分进行深入的化学分析。众所周知，前两种植物含有丰富的生物碱。第三种不富含生物碱，但用于民间医药，可用于分离其化学成分，包括萜类、黄酮类和木脂素。在研究中获得的纯化合物将被提交给NIH进行临床研究，并被提交给工业以测试可能的农业应用。经营范围：国际天然产物化学研究领域的专家。他与这位约旦科学家的合作研究可能会更好地了解正在研究的植物的化学成分，并促进美国和约旦科学家之间的更好合作，从而可能发现可能具有药理意义的化合物。

Description: This project supports participation by a scientist from the University of Jordan (Dr. M.H. Abu Zarga) in a research project with Dr. Maurice Shamma of the Chemistry Department, Pennsylvania State University to investigate the chemical contents of a variety of Jordanian plants. The plants will include Androcymbium palestinum, Colchicum decaisnei, and Paronychia argentea. The Jordanian scientist will spend about five months at Penn State for in-depth chemical analysis of these plants' contents. The first two plants are known to be rich in alkaloids. The third is not rich in alkaloids but is used in folk medicine and it is desirable to separate its chemical constituents including terpenoids, flavonoids and lignans. Pure compounds obtained in the research will be forwarded to NIH for their clinical research and to industry to test for possible agricultural applications. Scope: The PI is a world expert in the research on natural products' chemistry. His research in collaboration with the Jordanian scientist is likely to result in a better understanding of the chemistry of the plants being studied, and in better cooperation between scientists of the U.S. and Jordan which could lead to discovery of possible pharmacologically interesting compounds.