Acquisition of a High-Field Nuclear Mangetic Resonance Spectrometer

核磁共振（NMR）光谱是化学家用来研究分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。这项来自化学共享仪器项目的资助将帮助霍普学院（Hope College）芮研究所的化学系获得、操作和维护一台高场核磁共振光谱仪。该仪器的购置将加强本系培养本科生从事化学工作的能力，并将加强以下领域的研究：1)活性双金属早-晚过渡金属配合物2)1,2-dihydrocyclobutaıb！-萘-4,7-二酮及其衍生物3)从高粱和其他禾本科植物中提取的重要生物化合物的鉴定4)高粱中3-脱氧花青素的生物合成花青素生物合成模型5)二价锗、锡和铅化合物的异核磁共振波谱表征6)烯醇化物与环氧化物的非对映选择性反应7)环氧化物在双键和芳香位置上的竞争性环化反应。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. This award from the Chemistry Shared Instrumentation Program will help the Chemistry Department of the RUI institution, Hope College, to acquire, operate and maintain a high-field NMR spectrometer. The acquisition of the instrument will enhance the ability of the Department to prepare undergraduates for possible careers in chemistry and will enhance research in the following areas: 1) Reactive bi-metallic early-late-transition metal complexes 2) Preparation and polymerization of 1,2-dihydrocyclobutaıb!- napthalene-4,7-dione and derivatives 3) Identification of biologically important compounds exuded from sorghum and other grasses 4) Biosynthesis of 3-deoxyanthocyanidins in sorghum: a model for anthocyanidin biosynthesis 5) Characterization of divalent germanium, tin and lead compounds by heteronuclear NMR spectroscopy 6) Diastereoselective reactions of enolates with epoxides 7) Competitive cyclyzations of epoxides to double bonds and aromatic positions.