Acquisition of a High-Field Nuclear Mangetic Resonance Spectrometer

核磁共振波谱是化学家用来阐明分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这项来自化学共享仪器计划的奖项将帮助RUI机构希望学院的化学系获得、操作和维护一台高场核磁共振光谱仪。购买该仪器将加强该系为本科生可能从事化学工作做准备的能力，并将加强以下领域的研究：1)反应性双金属早-晚过渡金属配合物2)1，2-二氢环丁酸ı的制备和聚合3)高粱和其他牧草分泌物的鉴定4)高粱3-脱氧花青素的生物合成：花青素生物合成模型5)二价锗的表征，锡和铅化合物的异核核磁共振光谱6)烯醇酸盐与环氧化物的非对映选择性反应7)环氧化物到双键和芳香族位置的竞争环化反应。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. This award from the Chemistry Shared Instrumentation Program will help the Chemistry Department of the RUI institution, Hope College, to acquire, operate and maintain a high-field NMR spectrometer. The acquisition of the instrument will enhance the ability of the Department to prepare undergraduates for possible careers in chemistry and will enhance research in the following areas: 1) Reactive bi-metallic early-late-transition metal complexes 2) Preparation and polymerization of 1,2-dihydrocyclobutaıb!- napthalene-4,7-dione and derivatives 3) Identification of biologically important compounds exuded from sorghum and other grasses 4) Biosynthesis of 3-deoxyanthocyanidins in sorghum: a model for anthocyanidin biosynthesis 5) Characterization of divalent germanium, tin and lead compounds by heteronuclear NMR spectroscopy 6) Diastereoselective reactions of enolates with epoxides 7) Competitive cyclyzations of epoxides to double bonds and aromatic positions.