DNA Fingerprinting and Paternity Assessment in Non-Human Primates

非人类灵长类动物的 DNA 指纹图谱和亲子鉴定

• 批准号: 8818405
• 负责人: Mark Weiss
• 金额: $ 7.75万
• 依托单位: Wayne State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-02-01 至 1995-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8818405&HistoricalAwards=false
• 关键词: DNA; Fingerprinting; Paternity; Assessment; Non

The genome (the total of all genes in an organism) is much more variable than was thought a decade or two ago. This variability has led to the testing of gene loci to determine those which demonstrate a large number of alleles, none of which occur at high frequency. Such loci are used as "fingerprints" to distinguish individuals from each other and, because of their heritability, they are exceptionally useful in determining paternity. Thus, DNA fingerprinting is a relatively new and innovative technique that allows for identifications of parentage with an unprecedented degree of statistical confidence. Using DNS fingerprinting the investigators will determine paternity within captive populations of several species of nonhuman primates, and from a zone of hybridization of two species of baboons. The data generated in this study will allow for more efficient management of primate colonies by avoiding inbreeding, and will provide a tool for the investigation of a variety of questions relating kinship and selection, kin selection, dominance and reproductive success. The ability to identify parentage, especially paternity, is important in the management of primate colonies, and in field research on nonhuman primates.

基因组（生物体中所有基因的总和） 比一二十年前想象的要复杂。 这种可变性 导致了基因位点的测试，以确定那些 证明了大量的等位基因，其中没有一个发生在 高频率 这些基因座被用作“指纹”， 人与人之间的区别，因为 遗传性，它们在确定 亲子关系 因此，DNA指纹是一种相对较新的， 一种可以鉴定亲子关系的创新技术 以前所未有的统计信心。 使用DNS指纹，调查人员将确定 在几个物种的圈养种群中的父系 非人类灵长类动物，并从两个杂交区 狒狒的种类 本研究生成的数据将允许 为了更有效地管理灵长类动物群体， 近亲繁殖，并将提供一个工具，为调查一个 与亲属关系和选择有关的各种问题，亲属关系 选择、优势和繁殖成功。 的能力 确定亲子关系，特别是父亲身份，在 灵长类动物群体的管理，以及非人类的实地研究 灵长类动物