Flow Cytometer for Biochemical and Biomedical Engineering Research

用于生化和生物医学工程研究的流式细胞仪

• 批准号: 8906775
• 负责人: Larry McIntire
• 金额: $ 4.47万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-08-01 至 1990-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8906775&HistoricalAwards=false
• 关键词: Flow; Cytometer; Biochemical; Biomedical; Engineering

This is an instrumentation proposal for the acquisition of a flow cytometer. A unique characteristic of this instrument is its capability to measure cellular parameters at a single cell level. This is achieved by passing the cells in a single file through a flow chamber. Depending on the types of sensing devices that are installed with the instrument, various kinds of cellular components can be measured. The instrument will be shared by four research groups within the Department of Chemical Engineering at Rice University and includes interactions with investigators in Biochemistry at Rice, and several groups in cell biology at the Texas Medical Center. The research topics involved include: - Dynamics of immune systems - Study of host/plasmid interactions in recombinant populations - Stess effects on intracellular metabolism of mammalian cells - Receptor mediation of leukocyte/endothelial cell interactions - Characterization of population heterogeneity inhairy root cultures

这是一个仪器的建议，收购 流式细胞仪。 这其中的一个独特之处就是 仪器的一个优点是它能够测量细胞参数 在单个细胞水平上。这是通过传递 细胞在一个单一的文件通过流动室。 取决 安装的感应装置的类型， 仪器，各种类型的细胞成分可以 测定了 该仪器将由四个研究机构共享。 化学工程系内的小组， 莱斯大学，包括互动与 莱斯大学生物化学的研究人员， 德克萨斯医学中心的细胞生物学教授 研究 所涉及的课题包括： - 免疫系统动力学 - 重组质粒中宿主/质粒相互作用的研究 人口 - 应力对细胞内代谢的影响 哺乳动物细胞 - 白细胞/内皮细胞的受体介导 相互作用 - 群体异质性特征 无毛根培养