Collaborative Research: The Effects of Mating Structure on Phenotypic Variation and its Inheritance

合作研究：交配结构对表型变异及其遗传的影响

• 批准号: 8906956
• 负责人: Charles Goodnight
• 金额: $ 7.07万
• 依托单位: University of Vermont & State Agricultural College
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-06-15 至 1992-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8906956&HistoricalAwards=false
• 关键词: Collaborative; Research; Effects; Mating; Structure

The theoretical underpinnings of contemporary ecological genetics are mainly borrowed from the literature on quantitative genetics and the breeding of crop plants and domesticated animals. A number of fundamental issues remain to be resolved before the mapping of quantitative genetic methods from the realm of plant and animal breeding to the less controlled world of natural populations can be accomplished. One of the most serious difficulties in applying quantitative genetic methods to natural populations is that one of the assumptions of this approach is that the members of the population under study are mating at random. This is an assumption that is unlikely to be fulfilled in most natural populations. When there are complex forms of genetic variation, such as interactions among genes at different loci, violation of the assumption of random mating may have profound effects on the potential for evolutionary changes to occur. This research will use Plantago lanceolata to examine the role of population subdivision and localized mating in influencing estimates of the genetic variation in a population, and the potential for selection to bring about evolutionary change. The basic approach will be to compare genetic variance components estimated in a population by using the resemblance among relatives when the parents are chosen based on their probability of mating in the nature with similar estimates of genetic variance components when the parents are chosen at random from the population at large. If estimates of the genetic variance components under these two mating systems are different it will indicate that the mating structure can have a strong influence on the potential for evolutionary change to occur. If they are different the estimates based on localized mating, which are expected to be larger, will give the best predictions of the response to selection.

当代生态遗传学的理论基础主要来自数量遗传学以及作物和家养动物育种方面的文献。在完成从动植物育种领域到自然种群控制较少的世界的数量遗传方法图谱之前，仍有一些基本问题需要解决。将数量遗传学方法应用于自然种群最严重的困难之一是，这种方法的一个假设是被研究种群的成员是随机交配的。这是一个在大多数自然种群中不太可能实现的假设。当存在复杂形式的遗传变异时，例如不同基因座上的基因之间的相互作用，违反随机交配的假设可能会对发生进化变化的可能性产生深远的影响。这项研究将利用车前草来研究种群细分和局部交配在影响种群遗传变异估计方面的作用，以及选择带来进化变化的可能性。基本的方法是，当根据亲本在自然界中交配的概率选择亲本时，通过利用亲属之间的相似性来比较在种群中估计的遗传方差分量，与当从总体中随机选择亲本时，对遗传方差分量的类似估计。如果在这两种交配系统下对遗传方差分量的估计不同，这将表明交配结构可能对发生进化变化的可能性有很大影响。如果它们不同，基于局部交配的估计值预计会更大，这将给出对选择反应的最佳预测。