Dissertation Research: Genetic Variability and Interdemic Selection in Small Populations

论文研究：小群体的遗传变异和流行间选择

• 批准号: 9321689
• 负责人: Charles Goodnight
• 金额: $ 1万
• 依托单位: University of Vermont & State Agricultural College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-03-15 至 1996-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9321689&HistoricalAwards=false
• 关键词: Dissertation; Research; Genetic; Variability; Interdemic

9321689 Goodnight Inbreeding depression is potentially one of the most serious genetic consequences of reduced population size. This research is an empirical study on selection for reduced inbreeding depression among a subdivided population, using Tribolium castaneum as the model system. It will involve a comparison of two migration schemes, random and differential, among a set of fifteen inbred lineages derived from the same outbred stock population. In the differential migration scheme, migrants will be sent from lineages suffering from less inbreeding depression to lineages suffering from more inbreeding depression. In the random migration scheme, the rate of migration will be the same but migrants will be sent at random with respect to levels of inbreeding depression. A significant response to selection will be evident by a significant decrease in the level of inbreeding depression in the differential migration scheme, relative to the random migration scheme.%%% The significance of the research lies in its insight into the quantitative aspects of gene flow within and between small, subdivided populations, an issue of considerable significance to basic population and conservation biology.***

9321689 晚安 近亲繁殖衰退可能是种群规模减少所带来的最严重的遗传后果之一。 本研究是以赤拟谷盗为模型系统，对细分群体中减少近交衰退的选择进行的实证研究。 它将涉及对来自同一远交种群的十五个近交谱系中的两种迁徙方案（随机和差异）进行比较。 在差异化移民计划中，移民将从近亲繁殖衰退程度较低的谱系转移到近亲繁殖衰退程度较高的谱系。 在随机迁移计划中，迁移率将相同，但移民将根据近交衰退程度随机发送。 相对于随机迁移方案，差异迁移方案中的近交抑制水平显着降低，可以明显看出对选择的显着反应。%%%这项研究的意义在于它深入了解了小型细分种群内部和之间的基因流动的定量方面，这对基本种群和保护生物学具有重要意义。***