Nonadditive Genetic Variance: The Genetical Consequences of Population Structure

非加性遗传变异：种群结构的遗传后果

• 批准号: 9307694
• 负责人: Charles Goodnight
• 金额: $ 9.4万
• 依托单位: University of Vermont & State Agricultural College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-09-01 至 1996-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9307694&HistoricalAwards=false
• 关键词: Nonadditive; Genetic; Variance; Genetical; Consequences

9307694 Goodnight In recent years the effect of interactions among genes on evolution in structured populations has received increased attention. This is due to an appreciation of the ubiquity of structured populations, along with several recent studies that demonstrate that in subdivided populations gene interactions can have unique evolutionary consequences%%%% This research is a theoretical study using analytical and numerical approaches to investigate the effects of population structure, genetic drift, and selection when there are gene interactions. The analytical modes will examine the effects of genetic drift on the distribution of genetic variance in subdivided populations. Numerical simulation will be used to explore the effects of selection in subdivided populations. In addition, the simulations will be used to examine the role of gene interaction in the process of speciation.***

小行星9307694 近年来，基因间的相互作用对结构种群进化的影响越来越受到人们的关注。 这是由于人们对结构化群体的普遍存在的认识，以及最近的几项研究，沿着表明在细分群体中基因相互作用可能产生独特的进化后果% 本研究是一项理论研究，采用分析和数值方法来研究存在基因相互作用时种群结构、遗传漂变和选择的影响。 分析模式将研究遗传漂变对细分群体遗传方差分布的影响。 数值模拟将被用来探讨在细分群体的选择效果。 此外，模拟将用于研究基因相互作用在物种形成过程中的作用。