Purchase of a High Resolution Mass Spectrometer

购买高分辨率质谱仪

• 批准号: 8910501
• 负责人: Michael Zerner
• 金额: --
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-08-01 至 1990-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8910501&HistoricalAwards=false
• 关键词: Purchase; Resolution; Mass; Spectrometer

Mass spectral techniques such as Electron Impact (EI), Fast Atom Bombardment (FAB), and Chemical Ionization (CI) are used to probe intimate structural details and to obtain molecular compositions of a vast array of organic, bioorganic and organometallic compounds. Access to instrumentation capable of carrying out these state-of-the-art techniques is essential for the prosecution of frontier research in several fields of chemistry. The Department of Chemistry at the University of Florida will use this award from the Chemical Instrumentation Program to help acquire a mass spectrometer. The areas of chemical research that will be enhanced by the acquisition include the following: 1) Carbene complexes from rearrangement of transition metal sigma complexes and strained allenes: free and complexed to transition metals 2) Kinetic and stereochemical effects of fluorine substituents in thermal homolytic and pericyclic reactions 3) Heterocyclic cations, benzotriazole chemistry, thermolysis of organics, and polyvalent iodine derivatives 4) Synthetic studies of the ene reaction and samarium diiodide mediated reactions 5) Electrochemistry and mass spectrometry in the study of metabolic redox reactions mechanisms 6) Gas-phase reactions of metal complexes and monoclonal antibodies elicited against metal complexes.

质谱技术，如电子撞击（EI），快速原子轰击（FAB）和化学电离（CI）被用于探测内部结构细节，并获得大量有机，生物有机和有机金属化合物的分子组成。获得能够执行这些最先进技术的仪器对于在几个化学领域进行前沿研究是必不可少的。佛罗里达大学化学系将利用化学仪器项目的这一资助来帮助获得一台质谱仪。此次收购将加强化学研究的领域包括：1)过渡金属sigma配合物和张力烯重排的卡宾配合物；2)热均溶反应和周环反应中氟取代基的动力学和立体化学效应3)杂环阳离子、苯并三唑化学、有机物热裂解；4)烯反应和二碘化钐介导反应的合成研究5)代谢氧化还原反应机理的电化学和质谱研究6)金属配合物的气相反应及诱导的抗金属单克隆抗体复合物。