Purchase of a High Resolution Mass Spectrometer with HPLC for Shared Use

有了化学研究仪器和设施(CRIF)计划颁发的这一奖项，布法罗纽约州立大学化学系将获得一台带有高效液相色谱的高分辨率质谱仪。该设备将加强一些领域的研究，包括a)新催化方法的合成和开发；b)具有序列特异性和可调节稳定性的氢键分子双链的开发；c)用于核酸水解性切割的催化剂的设计；以及d)氨基酰-tRNA合成酶核酶的结构和功能的研究。质谱仪(MS)是一种用于探测大量有机、生物有机和有机金属分子的内部结构细节和获得其分子组成的技术。这些研究的结果将对一些领域产生影响，包括生物化学和工业过程催化剂的开发。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the State University of New York in Buffalo will acquire a High Resolution Mass Spectrometer with HPLC. This equipment will enhance research in a number of areas including a) the synthesis and development of new catalytic methods; b) development of hydrogen-bonded molecular duplexes with sequence-specificity and adjustable stability; c) design of catalysts for hydrolytic cleavage of nucleid acids; and d) studies of the structure and function of aminoacyl-tRNA synthetase ribozyme. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The results from these studies will have an impact in a number of areas including biochemistry and development of catalysts for industrial processes.