Purchase of a High Resolution Mass Spectrometer

化学研究仪器项目的这项奖励将帮助纽约大学化学系购买一台高分辨率质谱仪。将进行的研究包括：溶液和固体中的分子识别，固体主体-有机沸石，自组装主体，生物电子转移反应中的隧道效应，构象限制的新方法，研究α螺旋结构决定因素的合成肽模型，有机光化学，新的神经受体配体的合成，以及有机合成的主题。质谱仪(MS)是一种用于探测大量有机、生物有机和有机金属分子的内部结构细节和获得其分子组成的技术。电喷雾技术的加入将MS的范围扩展到蛋白质和核酸的相对分子质量，远远超过了任何其他技术。电喷雾电离与高分辨率相结合的使用提供了质谱学中可用的最新技术。它为化学家提供了表征化合物的最强大的工具之一。在质谱学中获得这种能力对于开展许多化学领域的前沿研究是至关重要的。

This award from the Chemistry Research Instrumentation Program will aid in purchasing a high resolution mass spectrometer for the Department of Chemistry at New York University. The research studies to be performed include the following: molecular recognition in solutions and solids, solid state host-organic zeolites, self assembling hosts, tunneling in biological electron transfer reactions, new methods for conformational restriction, synthetic peptide models for investigating the determinants of alpha helical structure, organic photochemistry, synthesis of new neuroreceptor ligands, and topics in organic synthesis. Mass Spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic and organometallic molecules. The addition of the technique of electrospray extends the range of MS to protein and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.