Purchase of a High Resolution Mass Spectrometer

该奖项来自化学研究仪器项目，将帮助纽约大学化学系购买一台高分辨率质谱仪。拟进行的研究包括以下内容：溶液和固体中的分子识别，固体宿主-有机沸石，自组装宿主，生物电子转移反应中的隧道，构象限制的新方法，用于研究α -螺旋结构决定因素的合成肽模型，有机光化学，新的神经受体配体的合成，有机合成的主题。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超出任何其他技术。电喷雾电离结合高分辨率提供了质谱分析的最新技术。它为化学家提供了表征化合物的最有力的工具之一。在质谱法中获得这种能力对于化学许多领域的前沿研究的进行是必不可少的。

This award from the Chemistry Research Instrumentation Program will aid in purchasing a high resolution mass spectrometer for the Department of Chemistry at New York University. The research studies to be performed include the following: molecular recognition in solutions and solids, solid state host-organic zeolites, self assembling hosts, tunneling in biological electron transfer reactions, new methods for conformational restriction, synthetic peptide models for investigating the determinants of alpha helical structure, organic photochemistry, synthesis of new neuroreceptor ligands, and topics in organic synthesis. Mass Spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic and organometallic molecules. The addition of the technique of electrospray extends the range of MS to protein and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.