Purchase of Low Resolution Tripe Quadrupole Mass Spectrometer

这份来自化学研究仪器和设施（CRIF）项目和多学科活动办公室（OMA）的合同将帮助哥伦比亚大学化学系获得一台低分辨率三重四极质谱计。该设备将加强许多领域的研究，包括仿生化学、天然产物合成、螺旋烯合成、功能配体和受体之间相互作用的阐明、分子识别和人工受体，以及天然产物的全合成。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超过任何其他技术。电喷雾电离结合高分辨率提供了质谱分析的最新技术。它为化学家提供了表征化合物的最有力的工具之一。在质谱法中获得这种能力对于化学许多领域的前沿研究的进行是必不可少的。

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at Columbia University to acquire a low resolution triple quadrupole mass spectrometer. This equipment will enhance research in a number of areas that include biomimetic chemistry, synthesis of natural products, synthesis of helicene, elucidation of the interaction between functional ligands and receptors, molecular recognition and artificial receptors, and total synthesis of natural products. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.