Purchase of Low Resolution Tripe Quadrupole Mass Spectrometer

购买低分辨率三极四极杆质谱仪

• 批准号: 9709066
• 负责人: Kenneth Eisenthal
• 金额: $ 19万
• 依托单位: Columbia University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9709066&HistoricalAwards=false
• 关键词: Purchase; Low; Resolution; Tripe; Quadrupole

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at Columbia University to acquire a low resolution triple quadrupole mass spectrometer. This equipment will enhance research in a number of areas that include biomimetic chemistry, synthesis of natural products, synthesis of helicene, elucidation of the interaction between functional ligands and receptors, molecular recognition and artificial receptors, and total synthesis of natural products. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.

该奖项由化学研究仪器和设施 CRIF计划和多学科活动办公室（OMA）将 协助哥伦比亚大学化学系获得 低分辨率三重四极质谱仪该设备将 加强包括仿生化学在内的多个领域的研究， 天然产物的合成，螺烯的合成， 功能配体和受体之间的相互作用，分子 识别和人工受体，以及天然 产品. 质谱（MS）是用于探测紧密结构的技术， 详细信息，并获得大量的分子组成， 有机、生物有机和有机金属分子。的加入 电喷雾技术将质谱的范围扩展到蛋白质和核酸 酸的分子量远远超过任何其他技术。使用 电喷雾电离结合高分辨率提供了 质谱分析的最新技术。它为化学家提供了 一个最强大的工具，可用于表征 化合物.在质谱分析中获得这种能力是 对许多领域的前沿研究至关重要， 化学.