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The proprotein convertases and their partners in health and disease

The proprotein convertases and their partners in health and disease
前蛋白转化酶及其在健康和疾病方面的伙伴
批准号：
332925
负责人：
Seidah Nabil G
金额：
$274.02万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=332925&lang=en
关键词：
Apoa5 Enzymology & Biochemistry Gene Expression & Regulation Hdl & Triglycerides Hypercholesterolemia/Inflammation/Neuropathology Knockout & Transgenic Mice Ldl Lipoprotein Metabolism & Atherosclerosis Lp(A) Lpl Microarrays & Mass Spectrometry

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中文摘要
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英文摘要
My team discovered and characterized a family of 9 enzymes, known as the proprotein convertases (PCs), key molecular scissors involved in producing the final forms of active proteins. Abnormal (higher/lower) activities of these enzymes can result in sever
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The unique and complementary functions of PCSK7 and PCSK9 in cardiometabolic health and disease
CRC Tier 1
  • 批准号：
    364795
  • 项目类别：
  • 资助金额：
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  • 财政年份：
    2016
  • 负责人：
    Seidah Nabil G
  • 依托单位：
    Universit de Montral
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