A Teacher Enhancement Program to Stimulate Laboratory-based Instruction in DNA Science for Advanced Placement and Honors Biology Classes

一个教师增强计划，以刺激基于 高级安置和荣誉的DNA科学指导 生物课 这项建议是为了支持分子遗传学研讨会 对288名生物学教师的分析 1990- 1992年夏天 模仿成功的 分子克隆课程，（TEI 87-51248），DNA科学 研讨会扩展了传统的研究生培训 冷泉港实验室的使命 水平 在为期一周的研讨会上，教师们制作和 使用以下技术分析重组DNA分子： DNA限制和连接，琼脂糖凝胶电泳， 微生物培养、细菌转化和质粒 隔离 一个周末的后续讲习班加强了 学习经验，并强调实践方面的 实施实验室教学计划。 目前NSF赞助的项目已经达到449个生物学 教师在12个国家资助的计划在加州，北 卡罗莱纳和威斯康星州。 统计分析记录了 显著的行为影响， 包括实验室教学，领导网络， 超过NSF资金的筹款活动 消耗。 NSF的支持得到了高度利用，形成了 可以说是对公众最大的承诺， 生物技术教育的任何机构在该国。 PI现在建议每年夏天举办四次研讨会， 288名高中教师将在 东南部和中西部。 三个“通勤者”讲习班 夏季将服务于大城市地区，而 “住宿”讲习班将针对来自一个 更广泛的地理区域。 我们还要求继续提供资金， 一项关于创新的纵向研究， 来自24个州的1,600名教师， 科学课程至今。 相当于NSF奖励的14.5%的金额正在被 作为费用分摊。

A Teacher Enhancement Program to Stimulate Laboratory-Based Instruction on DNA Science for Advanced Placement and Honors Biology Classes This proposal is to support workshops on molecular genetic analysis for 288 advanced placement/honors biology teachers during summers 1990-92. Modeled after the successful Molecular Cloning course, (TEI 87-51248), the DNA Science workshop extends the traditional postgraduate training mission of Cold Spring Harbor Laboratory to the secondary level. During the week-long workshops, teachers make and analyze a recombinant DNA molecule, using the techniques of DNA restriction and ligation, agarose gel electrophoresis, microbial culture, bacterial transformation, and plasmid isolation. A weekend follow-up workshop reinforces the learning experience and stresses the practical aspects of implementing a lab-teaching program. The current NSF-sponsored program has reached 449 biology teachers in 12 states-aided programs in California, North Carolina, and Wisconsin. Statistical analysis has documented significant behavioral effects among workshop participants, including lab teaching, leadership networking, and fundraising activities that more than match NSF funds expended. NSF support has been highly leveraged, forming the basis of what is arguably the largest commitment to public biotechnology education by any institution in the country. The PIs now propose to hold four workshops per summer that would reach an additional 288 high school teachers in the southeast and midwest. Three "commuter" workshops each summer would service large urban areas, while on "residential" workshop would target minority teachers from a wider geographic region. We also request funding to continue a substantial longitudinal study of innovation among the 1,600 teachers in 24 states who have been taught the DNA science curriculum to date. An amount equivalent to 14.5% of the NSF award is being contributed as cost-sharing.