Study of Reactive Intermediates by Static Solid State 13C and 15N Nuclear Magnetic Resonance at Cryogenic Temperatures

来自有机动力学项目的这笔赠款为犹他大学的大卫·M·格兰特博士的继续研究提供了支持。这项工作将为在非常低的温度下研究高度不稳定的分子物种的结构提供新的见解。格兰特博士将利用红外和核磁共振光谱学，结合量子力学计算，测量以前无法获得的高度应变分子和活性中间体的结构特征。调查的重点将是那些只能在惰性气体基质中的低温下分离出来的物种。将使用碳和氮同位素合成适当的双标记前体，以便最大限度地利用从光谱研究中获得的结构信息。

This grant from the Organic Dynamics Program provides support for the continuing research of Dr. David M. Grant at the University of Utah. This work will afford new insights into the structures of highly unstable molecular species that will be studied at very low temperatures. Dr. Grant will utilize infrared and nuclear magnetic resonance spectroscopy in combination with quantum mechanical calculations to measure previously inaccessible structural features of highly strained molecules and reactive intermediates. The investigation will focus on species that can only be isolated at cryogenic temperatures in an inert gas matrix. Appropriate doubly labeled precursors will be synthesized using both carbon and nitrogen isotopes in order to maximize the structural information obtained from the spectroscopic studies.