Aquisition of a Wide-Bore 600 MHz NMR Spectrometer
Aquisition of a Wide-Bore 600 MHz NMR Spectrometer
批准号:
0215774
负责人:
David Grant
金额:
$52.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-09-01 至 2005-08-31
中文摘要
获得重大研究仪器(MRI)计划的这一奖项后,犹他大学化学系将获得一台大口径600 MHz核磁共振光谱仪。该设备将使研究人员能够对a)天然产品、离子化合物、气溶胶和烟尘中的化学位移张量的测量,b)具有生物重要性的分子中的位移张量和耦合的四极相互作用,以及c)极化稀有气体中的自旋交换进行研究。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质,表征分子内原子的特定排列,并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说,获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对包括药物开发和先进材料在内的许多领域产生影响。
英文摘要
With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at the University of Utah will acquire a wide-bore 600 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) measurements of chemical shift tensors in natural products, ionic compounds, aerosols and soots, b) quadrupolar interactions in shift tensors and couplings in biologically important molecules, and c) spin exchange in polarized noble gases. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including drug development and advanced materials.
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