课题基金 / 基金详情

Defining and Developing Small Molecules and Targets to Address the role of Huntingtin in Oxidative DNA Damage Repair in Huntington's disease

Defining and Developing Small Molecules and Targets to Address the role of Huntingtin in Oxidative DNA Damage Repair in Huntington's disease
定义和开发小分子和靶标以解决亨廷顿蛋白在亨廷顿病氧化 DNA 损伤修复中的作用
批准号：
366556
负责人：
Truant Ray
金额：
$7.29万
依托单位：
McMaster University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-11-01 至 2017-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=366556&lang=en
关键词：
Ageing Cell Biology Cell Stress Computer Sorting Dna Repair High Content Analysis Huntington'S Disease Neurodegeneration Reactive Oxygen Species Rna Repair

项目摘要

项目成果

Truant Ray的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We have recently discovered that huntingtin protein, which is changed in Huntington's disease (HD) patients, is involved in repairing the "rusting" of DNA in the brain, but this is not happening properly in people with HD. We have been using advanced chem
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Defective DNA Damage Repair and Aberrant PARylation as a Mechanism of Mutant Huntingtin in Huntington's Disease
  • 批准号：
    408435
  • 项目类别：
    Operating Grants
  • 资助金额：
    $59.63万
  • 财政年份：
    2019
  • 负责人：
    Truant Ray
  • 依托单位：
    McMaster University
Elucidating the Protective Mechanism of Phospho-N17 Huntingtin in Huntington's disease
  • 批准号：
    238487
  • 项目类别：
    Operating Grants
  • 资助金额：
    $65.17万
  • 财政年份：
    2011
  • 负责人：
    Truant Ray
  • 依托单位：
    McMaster University
海外基金