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Elucidating the Protective Mechanism of Phospho-N17 Huntingtin in Huntington's disease

Elucidating the Protective Mechanism of Phospho-N17 Huntingtin in Huntington's disease
阐明磷酸-N17 亨廷顿蛋白对亨廷顿病的保护机​​制
批准号:
238487
负责人:
Truant Ray
金额:
$65.17万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01

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中文摘要
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英文摘要
Huntington's disease (HD) is one of a family of neurodegenerative diseases that occurs in mid-life that affects 1 in 6000. The exact cause of Huntington's disease is a mutation in the gene that codes for the huntingtin protein. From the last 5 years of CI
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Defective DNA Damage Repair and Aberrant PARylation as a Mechanism of Mutant Huntingtin in Huntington's Disease
  • 批准号:
    408435
  • 项目类别:
    Operating Grants
  • 资助金额:
    $59.63万
  • 财政年份:
    2019
  • 负责人:
    Truant Ray
  • 依托单位:
Defining and Developing Small Molecules and Targets to Address the role of Huntingtin in Oxidative DNA Damage Repair in Huntington's disease
  • 批准号:
    366556
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Truant Ray
  • 依托单位:
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