A New Strategy for Mild, Continuous Solution and Solid PhasePeptide Synthesis (U.S.-Egypt Cooperative Science; Science in Developing Countries)

温和、连续溶液和固相肽合成的新策略（美国-埃及合作科学；发展中国家的科学）

• 批准号: 9019461
• 负责人: Louis Carpino
• 金额: $ 2万
• 依托单位: University of Massachusetts Amherst
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-01 至 1993-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9019461&HistoricalAwards=false
• 关键词: New; Strategy; Mild; Continuous; Solution

Description: This proposal supports the collaboration of Dr. Louis A. Carpino, University of Massachusetts, and two faculty members (Drs. El-Sayed Mansour and Ahmed Kassem) and one graduate student (Mr. El-Faham) from the University of Alexandria, Egypt. Project funding will allow the team from the University of Alexandria to work for various periods of time in Dr. Carpino's laboratory and also allow Dr. Carpino a research visit to the University of Alexandria. Dr. Mansour, the senior member of the Egyptian team, will supervise research activities at the University of Alexandria and also spend three months at the University of Massachusetts conducting laboratory studies. Dr. Kassem will initiate work on the synthesis of FM ethers and Mr. El-Faham will work on N-FM peptide bond protection. Dr. Carpino, as Principal Investigator, will provide overall project supervision. Scope: This proposal brings together research scientists from two countries working in the area of peptide synthesis and coupling. It is anticipated that this collaborative research will result in novel techniques for the synthesis of insect hormone peptide segments. The Egyptian scientists will have the opportunity to become familiar with research techniques and equipment at the University of Massachusetts as well as contribute to the overall success of the project. Therefore, this proposal fulfills the objectives of the Science in Developing Countries Program in its exchange and transfer of scientific knowledge through an international collaboration.

说明：本提案支持以下方面的合作： Louis A.博士卡皮诺，马萨诸塞州大学，和两个 教师（El-Sayed Mansour和Ahmed Kassem博士） 和该大学的一名研究生（El-Faham先生） 亚历山大，埃及。 项目资金将允许团队 从亚历山大大学毕业， 在卡皮诺博士的实验室里呆了一段时间， 卡尔皮诺博士对大学进行了研究访问 亚历山大 曼苏尔博士，埃及的高级成员 该小组将监督大学的研究活动 在亚历山大的一所大学学习了三个月 马萨诸塞州实验室研究。 卡西姆博士 将启动FM醚的合成工作， El-Faham将致力于N-FM肽键保护。 博士 作为主要研究者，Carpino将提供 工程监理 范围：该提案汇集了研究科学家 来自两个国家从事多肽合成领域的研究 和耦合。 预计此次合作 研究将产生新的合成技术， 昆虫激素肽段的合成 埃及 科学家们将有机会熟悉 与研究技术和设备在大学的 马萨诸塞州以及贡献的整体成功 本项目 因此，该提案符合 发展中国家科学计划的目标 在交流和转让科学知识方面 通过国际合作。