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Impact of Early life MetaBolic and psychosocial strEss on susceptibility to mental Disorders; from converging epigenetic signatures to novel targets for therapeutic intervention

Impact of Early life MetaBolic and psychosocial strEss on susceptibility to mental Disorders; from converging epigenetic signatures to novel targets for therapeutic intervention
早期生活代谢和社会心理压力对精神障碍易感性的影响;
批准号:
387208
负责人:
Szyf Moshe
金额:
$5.46万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-06-01 至 2021-06-01

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中文摘要
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英文摘要
Each year 38.2% of the EU population suffers from a mental disorder. Extensive research on the biology of stress now shows that healthy development can be derailed by excessive or prolonged activation of stress response systems in the body and brain durin
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Targeted DNA demethylation based therapeutics.
  • 批准号:
    380053
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.22万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanism of action of DNMT1 inhibitors; a pharmacoepigenomic analysis
  • 批准号:
    259684
  • 项目类别:
    Salary Programs
  • 资助金额:
    $24.04万
  • 财政年份:
    2012
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
  • 批准号:
    229020
  • 项目类别:
    Operating Grants
  • 资助金额:
    $16.39万
  • 财政年份:
    2011
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanism of action of DNA methyltransferase (DNMT1) inhibitors and their therapeutic potential
  • 批准号:
    200288
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.62万
  • 财政年份:
    2010
  • 负责人:
    Szyf Moshe
  • 依托单位:
海外基金