Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
批准号:
229020
负责人:
Szyf Moshe
金额:
$16.39万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2014-03-01
中文摘要
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英文摘要
Liver cancer is the fifth common cancer in the world and is responsible for 0.5 million yearly deaths in China. There is no cure for liver cancer if detected late but the survival rate is high if it is discovered early. We have previously shown that live
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会议论文
Targeted DNA demethylation based therapeutics.
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依托单位:
Mechanism of action of DNA methyltransferase (DNMT1) inhibitors and their therapeutic potential
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Whole epigenome profiling of the epigenetic marks of maternal depression and its impact on the offspring epigenome.
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依托单位:
海外基金