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Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer

Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
DNA去甲基化抑制作为肝癌治疗策略的作用机制
批准号:
229020
负责人:
Szyf Moshe
金额:
$16.39万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2014-03-01

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中文摘要
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英文摘要
Liver cancer is the fifth common cancer in the world and is responsible for 0.5 million yearly deaths in China. There is no cure for liver cancer if detected late but the survival rate is high if it is discovered early. We have previously shown that live
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Targeted DNA demethylation based therapeutics.
  • 批准号:
    380053
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.22万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
  • 依托单位:
Impact of Early life MetaBolic and psychosocial strEss on susceptibility to mental Disorders; from converging epigenetic signatures to novel targets for therapeutic intervention
  • 批准号:
    387208
  • 项目类别:
    Operating Grants
  • 资助金额:
    $5.46万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanism of action of DNMT1 inhibitors; a pharmacoepigenomic analysis
  • 批准号:
    259684
  • 项目类别:
    Salary Programs
  • 资助金额:
    $24.04万
  • 财政年份:
    2012
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanism of action of DNA methyltransferase (DNMT1) inhibitors and their therapeutic potential
  • 批准号:
    200288
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.62万
  • 财政年份:
    2010
  • 负责人:
    Szyf Moshe
  • 依托单位:
海外基金