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Whole epigenome profiling of the epigenetic marks of maternal depression and its impact on the offspring epigenome.

Whole epigenome profiling of the epigenetic marks of maternal depression and its impact on the offspring epigenome.
母亲抑郁症表观遗传标记的整体表观基因组分析及其对后代表观基因组的影响。
批准号:
196312
负责人:
Szyf Moshe
金额:
$36.43万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-10-01 至 2012-10-01

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中文摘要
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英文摘要
Maternal depression has an impact on the health of a mother's offspring. However the mechanisms responsible for marking maternal adversity in the life history of the offspring are unknown. Although genetic transmission might be involved in a certain f
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Targeted DNA demethylation based therapeutics.
  • 批准号:
    380053
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.22万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
  • 依托单位:
Impact of Early life MetaBolic and psychosocial strEss on susceptibility to mental Disorders; from converging epigenetic signatures to novel targets for therapeutic intervention
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    387208
  • 项目类别:
    Operating Grants
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    $5.46万
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    2018
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    Szyf Moshe
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Mechanism of action of DNMT1 inhibitors; a pharmacoepigenomic analysis
  • 批准号:
    259684
  • 项目类别:
    Salary Programs
  • 资助金额:
    $24.04万
  • 财政年份:
    2012
  • 负责人:
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Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
  • 批准号:
    229020
  • 项目类别:
    Operating Grants
  • 资助金额:
    $16.39万
  • 财政年份:
    2011
  • 负责人:
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  • 依托单位:
海外基金