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Mechanism of action of DNMT1 inhibitors; a pharmacoepigenomic analysis

Mechanism of action of DNMT1 inhibitors; a pharmacoepigenomic analysis
DNMT1抑制剂的作用机制;
批准号:
259684
负责人:
Szyf Moshe
金额:
$24.04万
依托单位:
依托单位国家:
加拿大
项目类别:
Salary Programs
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-04-01 至 2017-04-01

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中文摘要
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英文摘要
Our genes that are inherited from our parents are marked by a chemical coating during gestation and are packaged in a highly organized manner in the nucleus of all cells. The chemical coating called "DNA methylation" and the packaging termed "chromatin mo
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Targeted DNA demethylation based therapeutics.
  • 批准号:
    380053
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.22万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
  • 依托单位:
Impact of Early life MetaBolic and psychosocial strEss on susceptibility to mental Disorders; from converging epigenetic signatures to novel targets for therapeutic intervention
  • 批准号:
    387208
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    Operating Grants
  • 资助金额:
    $5.46万
  • 财政年份:
    2018
  • 负责人:
    Szyf Moshe
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Mechanisms of action of DNA demethylation inhibition as a therapeutic strategy against liver cancer
  • 批准号:
    229020
  • 项目类别:
    Operating Grants
  • 资助金额:
    $16.39万
  • 财政年份:
    2011
  • 负责人:
    Szyf Moshe
  • 依托单位:
Mechanism of action of DNA methyltransferase (DNMT1) inhibitors and their therapeutic potential
  • 批准号:
    200288
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.62万
  • 财政年份:
    2010
  • 负责人:
    Szyf Moshe
  • 依托单位:
海外基金