Chemistry of Transition Metal/Main Group Element Compounds

过渡金属/主族元素化合物的化学

• 批准号: 9107489
• 负责人: John Gladysz
• 金额: $ 36.36万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-07-01 至 1994-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9107489&HistoricalAwards=false
• 关键词: Chemistry; Transition; Metal; Main; Group

This renewal award, made to the University of Utah in support of the research of Professor John Gladysz, deals with the structure, bonding, dynamic behavior and reactivity of transition metal/main group element complexes. Specifically, complexes of a chiral rhenium nitrosyl fragment with alkyl halides, amides, sulfides and sulfoxides will be prepared, characterized and their chemistry investigated. The chiral metal center will facilitate mechanistic studies and the development of applications in asymmetric organic synthesis. Alkyl halide complexes will be tested as asymmetric alkylation reagents, amide base complexes will be screened for asymmetric deprotonation and sulfide complexes will be screened for asymmetric oxidation to sulfoxides. %%% A comprehensive study of transition metal/main group element complexes will provide insights into their structure and reactivity patterns and possibly lead to a variety of applications such as precursors to solid-state materials and as catalysts or reagents for asymmetric organic synthesis.

这个更新奖，使犹他州大学的支持， 约翰·格拉迪斯教授的研究，涉及 结构、成键、动力学行为和反应性 过渡金属/主族元素配合物。 具体地说， 手性亚硝酰基片段与烷基的络合物 将制备卤化物、酰胺、硫化物和亚砜， 表征并研究其化学性质。手性 金属中心将促进机械研究和 不对称有机合成应用的发展。 卤代烷络合物将作为不对称烷基化进行测试 试剂，酰胺碱复合物将筛选不对称 去质子化和硫化物复合物将筛选 不对称氧化成亚砜。 %%% 过渡金属/主族元素的综合研究 复合物将提供对其结构的深入了解， 反应模式，并可能导致各种 例如固态材料的前体和作为 用于不对称有机合成的催化剂或试剂。