Synthesis of Ligands to Control Catalyst Homogeneity and Miscibility

控制催化剂均质性和混溶性的配体合成

• 批准号: 9222717
• 负责人: David Bergbreiter
• 金额: $ 26.4万
• 依托单位: Texas A&M Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-06-01 至 1997-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9222717&HistoricalAwards=false
• 关键词: Synthesis; Ligands; Control; Catalyst; Homogeneity

The focus of this research is the use of ligands to control catalyst homogeneity and miscibility. First, polymeric ligands will be prepared that have inverse temperature dependent solubility. The goal is to use a macromolecular ligand to both ligate a metal and to regulate a reaction. Second, oligomeric ligands will be designed to provide or contribute to the solvent microenvironment around a catalyst so that the effects of bulk solvent are mitigated. Third, macromolecules will be studied for the ability to phase isolate soluble species from one another in a common solvent. Finally, chiral macromolecular ligands that enhance stereoselectivity will be studied. %%% With this award, the Synthetic Organic Program is supporting the research of Dr. David E. Bergbreiter of the Department of Chemistry at Texas A&M University. Professor Bergbreiter will focus his work on using the properties of soluble macromolecules to design ligands that control the physical properties of homogeneous catalysts. The general idea is to learn if the physiochemical properties of soluble polymers can control a homogeneous catalyst's homogeneity and miscibility in useful ways.

本研究的重点是利用配体控制 催化剂的均匀性和分散性。 第一，聚合配体 将制备具有逆温度依赖性的 溶解度 我们的目标是使用一种大分子配体， 连接金属并调节反应。 二、寡聚 配体将被设计为提供或有助于 催化剂周围的溶剂微环境， 大量的溶剂被减轻。 第三，大分子将 研究了将可溶性物质从 在一种共同的溶剂中。 最后，手性 增强立体选择性的大分子配体将 研究了 %%% 有了这个奖项，合成有机计划正在支持 大卫E.伯格布赖特 德州农工大学化学系。 伯格布赖特教授将 他的工作重点是利用可溶性 大分子来设计控制物理 均相催化剂的性质。 总体思路是 了解可溶性聚合物的物理化学性质是否可以 控制均相催化剂的均匀性和分散性， 有用的方法。