New Roles for Soluble Polymers in Homogeneous Catalysis

德克萨斯农工大学化学系的David E. Bergbreiter教授，因其对可溶性聚合物在均相催化中的新作用的研究而受到有机和大分子化学项目的支持。通过设计具有可调溶解度的聚合物载体，Bergbreiter教授将开发方案，使聚合物结合催化剂易于分离、回收和再利用，用于各种金属催化反应，包括Heck反应、Suzuki偶联和烯烃异构化。多价聚合物间氢键将作为一种不溶性的、可回收的聚合物凝胶的形成方法进行研究。两种不同负载的催化剂或金属配合物的最小聚合物间相互作用的条件将通过变温31P核磁共振波谱来定义，这些研究也将为聚合物内络合提供见解。这些研究的结果，加上可溶性聚合物提供的溶解度控制，将用于开发新的催化剂测试组合方法。虽然可溶性催化剂比不溶性催化剂有许多优点，但它们通常很难从反应的期望产物中分离出来，这是一个关于产物污染和催化剂回收或再利用困难的问题。德克萨斯农工大学化学系的David E. Bergbreiter教授在有机和大分子化学项目的支持下，通过探索催化剂的聚合物载体，这些催化剂在所需的反应条件下是可溶的，但在适当的条件下，由于其详细的结构而变得不可溶或容易分离。以及聚合物结合催化剂在各种金属催化反应中的再利用。

Professor David E. Bergbreiter, of the Department of Chemistry at Texas A&M University, is supported by the Organic and Macromolecular Chemistry Program for his studies of new roles for soluble polymers in homogeneous catalysis. By designing polymer supports with tunable solubility, Professor Bergbreiter will develop schemes permitting the facile separation, recovery, and reuse of the polymer-bound catalysts for various metal-catalyzed reactions, including the Heck reaction, Suzuki coupling, and alkene isomerization. Polyvalent interpolymer hydrogen-bonding will be examined as an approach to the formation of insoluble, recoverable polymer gels. The conditions for minimal interpolymer interaction of two different supported catalysts or metal complexes will be defined by variable temperature 31P NMR spectroscopy, studies which will also provide insight into intrapolymer complexation. The results of these studies, coupled with the solubility control afforded by soluble polymers, will be used to develop new combinatorial approaches to catalyst testing.While soluble catalysts offer many advantages over their insoluble counterparts, they are often difficult to separate from the desired products of their reactions, a problem with regards to both contamination of the products and difficulty in recovery or reuse of the catalyst. By exploring polymeric supports for catalysts which are soluble under desired reaction conditions but are rendered insoluble or easily separable under appropriate conditions by their detailed structures, and with the support of the Organic and Macromolecular Chemistry Program, Professor David E. Bergbreiter, of the Department of Chemistry at Texas A&M University, is developing schemes permitting the facile separation, recovery, and reuse of polymer-bound catalysts for a variety of metal-catalyzed reactions.