Biphasic Catalysis Using Soluble Polymer Supports

使用可溶性聚合物载体的双相催化

• 批准号: 0952134
• 负责人: David Bergbreiter
• 金额: $ 42万
• 依托单位: Texas A&M Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-15 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0952134&HistoricalAwards=false
• 关键词: Biphasic; Catalysis; Using; Soluble; Polymer

The Chemical Catalysis Program supports Professor David E. Bergbreiter at Texas A&M University for a research project that will use phase-selectively soluble polymer-bound catalysts in immiscible solvent mixtures to address important challenges in synthesis and catalysis and will have an effect on the areas of catalysis, synthesis, Green chemistry and polymer chemistry. The proposed research will extend the PI's past discoveries on the use of polymer-bound catalysts in homogeneous solutions to conduct reactions in oil-in-oil emulsions. The catalyst immobilization chemistry proposed is based principally on the properties of the soluble polymer support. Using chemistry developed in prior work will allow the preparation of a variety of homogeneous catalysts, and phase segregate and concentrate them in the discontinuous phase of oil-in-oil emulsions. Transesterification catalysts, organometallic catalysts and organocatalysts will all be studied. The reactions to be studied are macrocyclizations using several different methods such as transesterification, olefin metathesis, Baylis-Hilman reactions, and carboxylic acid additions to epoxides.With the support of the Chemical Catalysis Program in the Chemistry Division at the National Science Foundation, Dr. Bergbreiter will perform research that will not only apply to multiple types of macrocyclizations (lactones, epoxides, Baylis-Hilmman), but also include careful and clever studies designed to optimize reaction rates, catalyst recovery, and removal of catalysts from products. Professor Bergbreiter?s work has also had an impact in the technology arena where earlier work was the basis of a recently described process by DuPont for a commercially viable route to clearcoats containing low volatile organic compounds (VOC) for automotive finishing applications. Broader impacts of this work include the training of undergraduate, PhD, and postdoctoral students. Professor Bergbreiter has had success introducing undergraduates both from Texas A&M and elsewhere to research. His research program is expected to continue to involve a significant percentage of students from underrepresented groups. The current program included 34% women and 38% students from underrepresented groups among the undergraduates or graduate students who worked on the project. These percentages will increase to 50% in the future by targeting schools in Texas that serve underrepresented groups. International outreach will be achieved by working with an undergraduate institution in Qatar, and with universities in Japan and Thailand, which will broaden the cultural experiences of his students.

化学催化项目支持德克萨斯a&m大学的David E. Bergbreiter教授的一项研究项目，该项目将在非混溶溶剂混合物中使用相选择性可溶性聚合物结合催化剂来解决合成和催化中的重要挑战，并将对催化、合成、绿色化学和聚合物化学领域产生影响。拟议的研究将扩展PI过去在均相溶液中使用聚合物结合催化剂在油中油乳液中进行反应的发现。提出的催化剂固定化化学主要基于可溶聚合物载体的性质。利用先前工作中发展的化学将允许制备各种均相催化剂，并在油中油乳液的不连续相中进行相分离和浓缩。交换催化剂，有机金属催化剂和有机催化剂都将进行研究。要研究的反应是用几种不同的方法进行的大环化反应，如酯交换反应、烯烃复分解反应、贝利斯-希尔曼反应和羧酸加到环氧化物中。在美国国家科学基金会化学部化学催化项目的支持下，Bergbreiter博士将进行的研究不仅适用于多种类型的大环化（内酯、环氧化物、贝利斯-希尔曼），还包括精心设计的巧妙研究，以优化反应速率、催化剂回收率和从产品中去除催化剂。Bergbreiter教授?他的工作也对技术领域产生了影响，早期的工作是杜邦公司最近描述的一种商业上可行的方法的基础，该方法用于汽车涂饰应用，该方法含有低挥发性有机化合物（VOC）。这项工作更广泛的影响包括培养本科生、博士和博士后。伯格布雷特教授已经成功地从德州农工大学和其他地方引进本科生来做研究。他的研究项目预计将继续有相当比例的学生来自代表性不足的群体。在参与该项目的本科生或研究生中，目前的项目包括34%的女性和38%来自代表性不足群体的学生。未来，这一比例将增加到50%，目标是德克萨斯州那些服务于代表性不足群体的学校。他将通过与卡塔尔的一所本科院校、日本和泰国的大学合作，实现国际推广，这将扩大他的学生的文化体验。