A Comprehensive Database of Nucleic Acid Structure

核酸结构综合数据库

• 批准号: 9305135
• 负责人: Helen Berman
• 金额: $ 91.1万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-06-01 至 1996-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9305135&HistoricalAwards=false
• 关键词: Comprehensive; Database; Nucleic; Acid; Structure

This award will support the continued development of the Nucleic Acid Database, a database of three-dimensional structures of nucleic acids and their intermolecular complexes. The goal is to devise an easily accessible and user friendly resource that serves a broad group of nucleic acid researchers. It is anticipated that the users of the database will include not only structural analysts such as crystallographers, theorists, and NMR spectroscopists, but also physical chemists who study macroscopic phenomena and molecular biologists who focus on the biological properties of these molecules. Substantial progress has been made in meeting the goal set three years ago in establishing the database; the available crystallographic data have been assembled, software has been developed to process and access the data, and the information is distributed electronically. The focus now is to make the database into a powerful research tool by providing methods for structure validation and structure prediction while at the same time making the primary and derivative data available to the scientific community.

该奖项将支持持续发展的 核酸 数据库，三维结构的数据库， 核酸和 它们的分子间复合物。 我们的目标是设计一个 方便和 用户友好的资源，服务于广泛的核 酸研究者 它 预计数据库的用户将包括 不仅是结构 分析师，如晶体学家，理论家和核磁共振 光谱学家，但 也是研究宏观现象的物理化学家 分子 生物学家专注于这些生物的生物学特性， 分子。 在实现既定目标方面取得了实质性进展 三年前在 建立数据库;可用的晶体学 数据已经 组装，软件已经开发，以处理和访问 数据并 信息以电子方式分发。现在的重点 是使 数据库成为一个强大的研究工具， 对于结构 验证和结构预测，同时 使初选 和衍生数据提供给科学界。