Charting the human brain connectome over the lifespan

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This project aims to develop neuroimaging reference charts for the human connectome and track the vast individual variability in brain connectivity across the life course. Connectomes will be mapped using tractography and diffusion magnetic resonance imaging data for 40,000 individuals, establishing the largest connectome biobank to date. Expected outcomes include an innovative lifespan brain charting platform, new paradigms to model individual brain variability and knowledge of how cognition, lifestyle and environment shape brain ageing. Brain charting will usher in a new era of precision connectomics, paving the way towards neuroscience-based personalisation of pathways in education, employment and wellbeing.