Purchase of Mass Spectrometry Data Systems

购买质谱数据系统

• 批准号: 9400607
• 负责人: David Dooley
• 金额: $ 10.93万
• 依托单位: Montana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-02-15 至 1995-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9400607&HistoricalAwards=false
• 关键词: Purchase; Mass; Spectrometry; Data; Systems

This award from the Chemistry Research Instrumentation and Facilities Program will aid in the purchase of mass spectrometry data systems in the Chemistry Department at Montana State University. The research to be performed with this instrumentation include the following: Studies of various high pressure gas phase ionic processes; the identification of the neutral products formed in gas phase ionic processes; fundamental studies of desorption ionization processes associated with FAB and Electrospray mass spectrometry; the detection of environmentally interesting atmospheric components at the low- and sub- parts per trillion level; organic transformations facilitated by platinum(II) and other transition metals; biological control and signalling mechanisms involving macromolecular receptors in visual and neutrophil systems; the production of Taxol and Taxanes from microbiological sources; and the identification of lipid peroxidation products generated by environmental toxins. Mass Spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic and organometallic molecules. The computer data systems allow state-of-the-art control of research grade mass spectrometers which gives the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.

这份来自化学研究仪器和设施项目的合同将帮助蒙大拿州立大学化学系购买质谱数据系统。使用该仪器进行的研究包括：各种高压气相离子过程的研究；气相离子过程中中性产物的鉴定；与FAB和电喷雾质谱相关的脱附电离过程的基础研究；在低万亿分之一和万亿分之一以下水平检测环境感兴趣的大气成分；铂（II）和其他过渡金属促进有机转化；视觉和中性粒细胞系统中涉及大分子受体的生物控制和信号传导机制；从微生物来源生产紫杉醇和紫杉烷；以及环境毒素产生的脂质过氧化产物的鉴定。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。计算机数据系统允许对研究级质谱仪进行最先进的控制，这为化学家表征化合物提供了最强大的工具之一。在质谱法中获得这种能力对于化学许多领域的前沿研究的进行是必不可少的。