International Postdoctoral Fellows Program: Dynamics and Pinning of Spiral Wave Defects in Active Media

9406090贝尔蒙特该奖项是根据国际初级研究员和博士后研究员计划颁发的，该计划使美国科学家和工程师能够在国外公认的卓越研究中心进行为期3至12个月的研究。该项目的奖项提供了联合研究的机会，并提供了使用国外独特或互补的设施、专业知识和实验条件的机会。这一奖项将支持安德鲁·L·贝尔蒙特博士为期12个月的博士后研究访问，与豪尔赫·R·特雷迪奇博士在Nice研究所合作。贝尔蒙特博士建议研究螺旋波缺陷的运动，开发通过抑制受控区域的化学反应来吸引和保持它们的方法，并测量这种“钉扎”的强度。他还建议探索这些缺陷的产生和破坏，以及它们受到复杂边界条件和各向异性或非均匀介质的扰动。这种螺旋缺陷的解除或中断将对心脏的室颤(导致猝死)的动力学产生重要的影响，这被认为是由肌肉中被钉扎的螺旋电波所引起的。***

9406090 Belmonte This award is under the International Junior Investigator and Postdoctoral Fellows Program, which enables U.S. scientists and engineers to conduct three to twelve months of research abroad at research centers of proven excellence. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a twelve-month postdoctoral research visit by Dr. Andrew L. Belmonte to work with Dr. Jorge R. Tredicce at the Institut NonLineaire de Nice. Dr. Belmonte proposes to study the motion of spiral wave defects, developing methods to attract and hold them by suppression of chemical reactivity in controlled regions, and measuring the strength of this "pinning." He also proposes to explore the creation and disruption of these defects, and their perturbation by complex boundary conditions and anisotropic or inhomogeneous media. The unpinning or disruption of such spiral defects would have important implications for the dynamics of ventricular fibrillation in the heart (leading to sudden death), which is thought to be caused by pinned spiral waves of electrical excitation in the muscle. ***