Acquisition of a 300 MHz NMR Instrument

CTS-9413698埃里克·贝克曼这项建议是用布鲁克公司制造的AMX300 MHz仪器部分取代用于液体和固体的激励式MSL 300 MHz核磁共振仪器。现有仪器的磁铁、前置放大器和高功率放大器将被保留，而控制台、计算机和磁盘驱动器将被更换。此外，还将获得新的探测头目。虽然MSL300仪器对该大学正在进行的许多研究项目至关重要，但由于经常需要维修和更换部件，维护成本已经变得令人望而却步。此外，获得合适的零部件本身也变得越来越困难。最后，制造商没有为这种类型的仪器提供新的软件，因为它为较新的型号提供了新的软件。目前正在进行的主要研究领域包括材料合成、重分子(特别是煤渣和石油渣，单独或以共处理方案)的加工，以及催化，包括催化剂的表征。核磁共振分析在材料、产品和催化剂的结构研究、机理确定、反应动力学研究和各种过程的开发中发挥着至关重要的作用，是匹兹堡唯一具有MAS能力(即可以分析固体样品)的仪器。目前使用核磁共振的研究是由NSF、美国能源部、美国环保局、美国能源部和许多工业企业赞助的，包括迈尔斯、卡尔贡和西屋等当地公司。1994年，有16名研究生在首席调查员的指导下进行这项研究，他们需要在研究中使用核磁共振仪器。除了支持他们的研究项目，独特的仪器，如MAS-核磁共振，为研究生和本科生提供了宝贵的培训经验。从1990年到现在，Co-Pi一直担任核磁共振设施的负责人，负责维护、维修和用户调度。目前的核磁共振仪器每周至少使用六天，可供大学内外的研究人员使用。

ABSTRACT CTS-9413698 Eric Beckman This proposal is for the partial replacement of an exciting MSL 300MHz Nuclear Magnetic Resonance (NMR) instrument used for both liquids and solids, with an AMX 300MHz instrument manufactured by Bruker. The magnet, preamplifiers and high power amplifiers of the existing instrument will be retained, while the console, computer, and disk drives will be replaced. Further, new probeheads will be acquired. The MSL300 instrument while vital to many research programs ongoing at the University, has reached the point where maintenance costs have become prohibitively expensive because of the frequent need for repairs and replacement of parts. Further, obtaining the right parts has itself become increasingly difficult. Finally, the manufacturer does not provide new software for this type of instrument, as it does for newer models. The main areas of research currently underway involve materials synthesis, processing of heavy molecules (particularly coal and petroleum resid, individually or in co-processing schemes), and catalysis, including characterization of catalysts. The NMR analyses play an essential role in the structural studies of materials, products, and catalysts, in determinations of mechanism, in kinetic studies of reactions, and in the development of various processes, and is the only instrument with MAS capability (i.e. which can analyze solid samples) in Pittsburgh. Research which currently employs the NMR is sponsored by NSF, DOE, EPA, DOD, and a number of industrial concerns, including local companies such as Miles, Calgon, and Westinghouse. In 1994, sixteen graduate students, working under the supervision of the Principal Investigators on this proposal, need to use the NMR instrument in their research. In addition to supporting their research projects, unique instruments such as the MAS-NMR provide invaluable training experiences for graduate and undergraduate students. From 1990 to the present, the Co-PI has been the director of th e NMR facility, responsible for maintenance, repair, and user scheduling. The current NMR instrument is in use at least six days per week and is made available to researchers both within and from outside the University.