MRI: Acquisition of a 300 MHz Nuclear Magnetic Resonance (NMR) Spectrometer to Enhance Research and Education at Ursinus College

该奖项由重大研究仪器(MRI)和化学研究仪器和设施(CRIF)计划支持。乌尔辛斯学院的瑞安·沃尔沃德教授及其同事马克·埃里森和阿曼达·雷格正在获取一台400兆赫的核磁共振(核磁共振)光谱仪。总的来说，核磁共振波谱是化学家研究分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中变化的相互作用。这些核磁共振研究的结果对合成有机/无机化学、材料化学、法医学和生物化学产生了影响。该仪器是本科生通过独立的学生研究和传统的学术课程进行的教学和研究的组成部分。学生们在独立学习和暑期研究期间从事这些项目。该光谱仪通过建立一个创新和发现中心，补充了最近科学基础设施的改进。这台核磁共振光谱仪加强了各级的研究和教育。它帮助研究人员合成基于小分子荧光的化学工具来检测水污染物。它用于结构表征和分析修饰的金属结合蛋白的氧依赖反应性。该光谱仪还用于分析用作抗生素输送材料的功能化单壁碳纳米管。

This award is supported by the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) Programs. Professor Ryan Walvoord from Ursinus College and colleagues Mark Ellison and Amanda Reig are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the structural studies of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the changing interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework. Students work on these projects during independent studies and summer research. The spectrometer complements recent infrastructure improvements in the sciences with the construction of an Innovation and Discovery Center.This NMR spectrometer enhances research and education at all levels. It aids researchers in synthesizing small molecule fluorescence-based chemical tools for the detection of water contaminants. It is used to structurally characterize and analyze oxygen-dependent reactivity of modified metal-binding proteins. The spectrometer is also used in the analysis of functionalized single-wall carbon nanotubes to be used as delivery materials for antibiotics.