MRI: Acquisition of a 300 MHz Nuclear Magnetic Resonance (NMR) Spectrometer to Enhance Research and Education at Ursinus College

该奖项由主要研究仪器（MRI）和化学研究仪器和设施（CRIF）项目支持。乌尔西纳学院的瑞恩·沃尔沃德教授和他的同事马克·埃里森和阿曼达·瑞格正在购买一台400兆赫的核磁共振光谱仪。总的来说，核磁共振波谱是化学家用于分子结构研究的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液或固体状态下分子之间相互作用的变化。这些核磁共振研究的结果对合成有机/无机化学、材料化学、法医学和生物化学都有影响。该仪器是本科学生通过独立学生研究和传统学术课程进行教学和研究的一个组成部分。学生在独立学习和暑期研究期间完成这些项目。光谱仪补充了最近科学基础设施的改进与创新和发现中心的建设。这种核磁共振光谱仪增强了各级的研究和教育。它帮助研究人员合成用于检测水污染物的小分子荧光化学工具。它用于结构表征和分析修饰的金属结合蛋白的氧依赖反应性。该光谱仪还用于分析用作抗生素递送材料的功能化单壁碳纳米管。

This award is supported by the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) Programs. Professor Ryan Walvoord from Ursinus College and colleagues Mark Ellison and Amanda Reig are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the structural studies of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the changing interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework. Students work on these projects during independent studies and summer research. The spectrometer complements recent infrastructure improvements in the sciences with the construction of an Innovation and Discovery Center.This NMR spectrometer enhances research and education at all levels. It aids researchers in synthesizing small molecule fluorescence-based chemical tools for the detection of water contaminants. It is used to structurally characterize and analyze oxygen-dependent reactivity of modified metal-binding proteins. The spectrometer is also used in the analysis of functionalized single-wall carbon nanotubes to be used as delivery materials for antibiotics.