MRI: Acquisition of a 300 MHz Nuclear Magnetic Resonance (NMR) Spectrometer to Enhance Research and Education at Ursinus College

MRI：购买 300 MHz 核磁共振 (NMR) 波谱仪以加强乌尔西努斯学院的研究和教育

基本信息

批准号：
1726836
负责人：
Ryan Walvoord
金额：
$ 21.43万
依托单位：
Ursinus College
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-01 至 2020-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1726836&HistoricalAwards=false
关键词：
MRI Acquisition 300 MHz Nuclear

项目摘要

This award is supported by the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) Programs. Professor Ryan Walvoord from Ursinus College and colleagues Mark Ellison and Amanda Reig are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the structural studies of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the changing interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework. Students work on these projects during independent studies and summer research. The spectrometer complements recent infrastructure improvements in the sciences with the construction of an Innovation and Discovery Center.This NMR spectrometer enhances research and education at all levels. It aids researchers in synthesizing small molecule fluorescence-based chemical tools for the detection of water contaminants. It is used to structurally characterize and analyze oxygen-dependent reactivity of modified metal-binding proteins. The spectrometer is also used in the analysis of functionalized single-wall carbon nanotubes to be used as delivery materials for antibiotics.

该奖项得到了主要的研究工具（MRI）和化学研究工具和设施（CRIF）计划的支持。来自Ursinus学院和同事Mark Ellison和Amanda Reig的Ryan Walvoord教授正在收购400 MHz核磁共振（NMR）光谱仪。通常，NMR光谱是化学家可用于分子结构研究的最强大工具之一。它用于识别未知物质，以表征分子内原子的特定排列，并研究溶液中分子或固态中分子之间不断变化的相互作用。这些NMR研究的结果对合成有机/无机化学，材料化学，取证和生物化学的影响有影响。该乐器是教学的组成部分，也是本科生通过独立学生研究和传统学术课程进行的研究。学生在独立研究和夏季研究期间从事这些项目。光谱仪通过建立创新和发现中心的构建来补充科学的最新基础设施改进。此NMR光谱仪可增强各个级别的研究和教育。它有助于研究人员合成基于荧光的小分子化学工具，以检测水污染物。它用于在结构上表征和分析改良金属结合蛋白的氧依赖性反应性。光谱仪还用于分析官能化的单壁碳纳米管，以用作抗生素的递送材料。