MRI: Acquisition of a 300 MHz Nuclear Magnetic Resonance (NMR) Spectrometer to Enhance Research and Education at Ursinus College

该奖项由主要研究仪器（MRI）和化学研究仪器和设施（CRIF）计划支持。来自乌尔西诺学院的Ryan Walvoord教授及其同事Mark Ellison和阿曼达Reig正在获得一台400 MHz核磁共振（NMR）光谱仪。一般来说，NMR光谱学是化学家用于分子结构研究的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间不断变化的相互作用。 这些NMR研究的结果对合成有机/无机化学、材料化学、法医学和生物化学产生了影响。该仪器是教学的一个组成部分，以及由本科生通过独立的学生研究和传统的学术课程进行研究。学生在独立学习和夏季研究期间从事这些项目。该光谱仪通过创新和发现中心的建设补充了科学领域最近的基础设施改进。该NMR光谱仪增强了各级研究和教育。它帮助研究人员合成小分子荧光化学工具，用于检测水污染物。 它用于结构表征和分析修饰的金属结合蛋白的氧依赖性反应性。该光谱仪还用于分析功能化的单壁碳纳米管，用作抗生素的输送材料。

This award is supported by the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) Programs. Professor Ryan Walvoord from Ursinus College and colleagues Mark Ellison and Amanda Reig are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the structural studies of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the changing interactions between molecules in solution or in the solid state. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework. Students work on these projects during independent studies and summer research. The spectrometer complements recent infrastructure improvements in the sciences with the construction of an Innovation and Discovery Center.This NMR spectrometer enhances research and education at all levels. It aids researchers in synthesizing small molecule fluorescence-based chemical tools for the detection of water contaminants. It is used to structurally characterize and analyze oxygen-dependent reactivity of modified metal-binding proteins. The spectrometer is also used in the analysis of functionalized single-wall carbon nanotubes to be used as delivery materials for antibiotics.