Dissertation Research: Population Genetic Analysis of Paleoasiatic-Speaking Peoples of Northeastern Siberia: Evolutionary and Historical Influences

利用线粒体DNA变异来评估人类种群的遗传变异并重建人类迁移模式的效用已被许多研究证明，这可以追溯到著名的“夏娃”假说。由于这个原因，最近对新世界和亚洲人类起源的调查使用了mtDNA变异来追踪这些地区人群之间的遗传联系。虽然很明显，新世界的人口来自北亚人口，但进入新世界的移民有多少，以及有多少原始人口（不同的说法是一次，三次，甚至四次单独的移民）并不清楚。要解决这些问题，需要对北亚人口进行分析。这个从西伯利亚人群中收集和分析样本的项目是及时的，将为进一步调查这些问题提供关键信息。该研究生之前在该领域有实地经验，并为收集样本奠定了基础，精通分析技术，并已与人合作撰写了该领域的重要论文。该项目将返回重要和有趣的信息。* * *

9414900 Wallace, Douglas The utility of using mitochondrial DNA variation to assess genetic variation in human populations and to reconstruct human migration patterns has been demonstrated by many studies, going back to the well-known "Eve" hypothesis. For this reason, recent investigations of human origins in the New World and Asia have used mtDNA variation to trace genetic links between populations in these regions. While it is clear that New World populations are derived from northern Asian populations, it is not so clear how many migrations there were into the New World, and from how many source populations (variously argued as one, three, or even four separate migrations). Analysis of northern Asian populations is required to address these issues. This project to collect and analyze samples from Siberian populations is timely and will provide critical information for further investigation of these issues. The graduate student has previous field experience in this area, and has established the groundwork for collecting the samples, is well versed in the analytic techniques, and has alrealy co- authored important papers in this area. The project will return important and intersting information. ***