Dissertation Research: Population Genetic Analysis of Paleoasiatic-Speaking Peoples of Northeastern Siberia: Evolutionary and Historical Influences

9414900 道格拉斯？华莱士 利用线粒体DNA变异来评估人类群体的遗传变异和重建人类迁移模式的效用已被许多研究所证明，可以追溯到众所周知的“夏娃”假说。 因此，最近对新大陆和亚洲人类起源的研究使用mtDNA变异来追踪这些地区人群之间的遗传联系。 虽然新大陆的人口显然来自北方亚洲人口，但不清楚有多少移民进入新大陆，以及有多少来源人口（不同的说法是一个，三个，甚至四个独立的移民）。 需要对北方亚洲人群进行分析以解决这些问题。 该项目收集和分析西伯利亚人群的样本是及时的，将为进一步调查这些问题提供关键信息。 该研究生在这一领域有过实地工作经验，并为收集样品奠定了基础，精通分析技术，并在这一领域合著了重要论文。 该项目将返回重要和有趣的信息。 ***

9414900 Wallace, Douglas The utility of using mitochondrial DNA variation to assess genetic variation in human populations and to reconstruct human migration patterns has been demonstrated by many studies, going back to the well-known "Eve" hypothesis. For this reason, recent investigations of human origins in the New World and Asia have used mtDNA variation to trace genetic links between populations in these regions. While it is clear that New World populations are derived from northern Asian populations, it is not so clear how many migrations there were into the New World, and from how many source populations (variously argued as one, three, or even four separate migrations). Analysis of northern Asian populations is required to address these issues. This project to collect and analyze samples from Siberian populations is timely and will provide critical information for further investigation of these issues. The graduate student has previous field experience in this area, and has established the groundwork for collecting the samples, is well versed in the analytic techniques, and has alrealy co- authored important papers in this area. The project will return important and intersting information. ***