Modernization of Advanced Instrumentation Area; Renovation of Research Space and Greenhouse

先进仪器仪表领域的现代化；

• 批准号: 9415244
• 负责人: David Beveridge
• 金额: $ 43.43万
• 依托单位: Wesleyan University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-07-01 至 1997-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9415244&HistoricalAwards=false
• 关键词: Modernization; Advanced; Instrumentation; Area; Renovation

Wesleyan University is the recipient of funds from the Academic Research Infrastructure Program to repair, renovate and modernize key facilities for research and research training in chemistry and the life sciences. Specifically, a large moribund spectroscopy research laboratory will be modernized into a multipurpose advanced instrumentation facility, and selected research laboratories and a greenhouse will be renovated. The effected laboratories are located in the basement and ground floors of the connected Hall-Atwater and Shanklin buildings that comprise part of the Wesleyan Science Center. The advanced instrumentation facility will support research initiatives in physical chemistry, biochemistry and molecular biophysics. Investigative projects that will benefit from the renovations include: NMR studies of the structure and base pair opening events in nucleic acids and NMR studies of damaged DNA, molecular dynamics of DNA and protein-DNA interactions, studies of chemical intermediates in total synthesis, electrochemical mechanistic and synthetic studies, and EPR studies of metalloproteins and model complexes. In a parallel initiative, in conjunction with faculty development in the area of plant genetics and evolutionary biology, the greenhouse and related research space in the Biology Department will be upgraded and renovated to support research in ecophysical and evolutionary studies of plant phenotypic plasticity. Renovations will involve reconfiguring space, upgrading mechanical, electrical, environmental control, and plumbing systems; and installing benches and fixed cabinetry in research laboratories. The improvements for the greenhouse will consist of resurfacing concrete floors, replacing defunct vent motors, actuators, and pad coolers; cleaning and re-sealing the glazing of windows; providing emergency power, and prep and equipment areas. The renovations will have several immediate implications including the consolidation of advanced instruments in a centralized location that will create a locus of research activity. The renovated laboratories will provide a modern environment for faculty, graduate and undergraduate students to conduct research, and will foster collaborative interactions among research personnel across disciplinary lines.

卫斯理大学获得了学术研究基础设施计划的资金，用于修复、翻新和现代化化学和生命科学领域的研究和研究培训的关键设施。 具体来说，一个大型的、濒临倒闭的光谱学研究实验室将被现代化改造为一个多功能的先进仪器设施，并且选定的研究实验室和一个温室将被翻新。 受影响的实验室位于相连的 Hall-Atwater 和 Shanklin 建筑的地下室和底层，这些建筑构成卫斯理科学中心的一部分。 先进的仪器设施将支持物理化学、生物化学和分子生物物理学的研究计划。 受益于改造的研究项目包括：核酸结构和碱基对打开事件的核磁共振研究、受损DNA的核磁共振研究、DNA分子动力学和蛋白质-DNA相互作用、全合成中的化学中间体研究、电化学机理和合成研究，以及金属蛋白和模型复合物的EPR研究。 在一项并行举措中，结合植物遗传学和进化生物学领域的教师发展，将对生物系的温室和相关研究空间进行升级和翻新，以支持植物表型可塑性的生态物理和进化研究。 翻新工程将涉及重新配置空间、升级机械、电气、环境控制和管道系统；在研究实验室安装长凳和固定橱柜。 温室的改进将包括重新铺设混凝土地板，更换失效的通风电机、执行器和湿帘冷却器；清洁并重新密封窗户玻璃；提供应急电源以及准备和设备区域。 此次翻修将产生几个直接影响，包括将先进仪器整合到一个集中位置，从而创建一个研究活动场所。翻新后的实验室将为教师、研究生和本科生提供现代化的研究环境，并将促进跨学科研究人员之间的协作互动。