I-Corps: Imaging Software for Long-Bone Fracture Alignment

I-Corps：用于长骨骨折对齐的成像软件

• 批准号: 2226489
• 负责人: Mohammad Abedin Nasab
• 金额: $ 5万
• 依托单位: Rowan University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2226489&HistoricalAwards=false
• 关键词: Corps; Imaging; Software; Long; Bone

The broader impact/commercial potential of this I-Corps project is the development of a software-driven visual aid for surgeons treating femur fractures to improve alignment and prevent reoperations. Approximately 350,000 proximal femur fractures and 65,000 femur shaft fractures occur in the United States annually. Due to the aging population, this number of fractures is increasing and is anticipated to double by the year 2050. Current surgical procedures are manual, and surgeons experience a myriad of complications to align femur fractures, including difficulty in achieving accurate reduction, subsequent malalignment of bone fragments, high x-ray radiation, nonunion complications, and soft tissue damage. Malalignment is a serious complication with long-bone fractures, with a malalignment of 15° or more after femur fracture fixation occurring in 28% of patients. Using the proposed imaging software, the surgeon may have more accurate vision and be able to track the position of the bone fragments during the surgery. The tracking system may prevent the trial-and-error approach for fracture alignment and reduce the time of the surgery. By using the proposed imaging software, the surgeon may check the length and rotation of the aligned bone intraoperatively, which may prevent malalignment and subsequent reoperations.This I-Corps project is based on the development of an imaging software to aid long-bone fracture surgery to improve alignment and prevent reoperations. Using the proposed imaging software, surgeons may have a precise sense of the bone segments' positions in space relative to each other. Optical trackers are used to find the position of 2 rods that are attached to the distal and proximal bone fragments. Image registration is then performed on the X-ray images to find the exact three dimensional (3D) position of the bone segments. In addition, computer tomography data of the unbroken bone is used to providing data to align the fractured bone. Using the proposed imaging software, the surgeon may track the bone position in real-time while manipulating the bone into the final desired position guided by the image of the healthy bone. This 3D vision may provide an advantage for surgeons in comparison to the 2D X-ray images that are used today to check the bone position and alignment.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛的影响/商业潜力是开发软件驱动的视觉援助，用于治疗股骨碎片以改善对准并防止重新操作的外科医生。每年在美国发生大约350,000个近端股骨碎片和65,000个股骨轴碎片。由于人口老龄化，这种骨折数量的增加，预计到2050年将翻一番。当前的手术是手动的，外科医生经历了无数的并发症，以使股骨碎片保持一致，包括难以实现准确的减少，随后的骨骼碎片的恶意症状，X射线碎片，高X射线辐射，骨辐射，降低，骨骼辐射，损坏和软组织损坏。 Malaligon是一种严重的并发症，具有长骨碎片，在28％的患者中发生股骨碎片固定后，骨化15°或更多。使用所提出的成像软件，外科医生可能具有更准确的视力，并且能够在手术过程中跟踪骨碎片的位置。跟踪系统可能会阻止试验方法的碎片对齐方式并减少手术时间。通过使用所提出的成像软件，外科医生可以在术中检查对齐的骨骼的长度和旋转，这可能会阻止错位和随后的重新操作。该I-Corps项目基于成像软件的开发，以帮助长骨碎片手术以改善对齐状态并防止重新操作。使用所提出的成像软件，外科医生可能对骨骼片段在彼此中的位置具有精确的感觉。光学跟踪器用于找到附着在独特和代理骨碎片上的2个杆的位置。然后在X射线图像上进行图像注册，以找到骨段的精确三维（3D）位置。此外，使用不间断的骨头的计算机断层扫描数据用于提供数据以对齐碎片的骨头。使用拟议的成像软件，外科医生可以实时跟踪骨骼位置，同时将骨头操纵到由健康骨骼图像引导的最终所需位置。与当今用于检查骨位置和对齐的2D X射线图像相比，这种3D视觉可能为外科医生提供了优势。该奖项反映了NSF的法定任务，并通过评估基金会的知识分子优点和更广泛的影响来审查标准。