High Q Single Crystal Cantilevers for Magnetic Resonance Force Microscopy

用于磁共振力显微镜的高 Q 单晶悬臂梁

基本信息

  • 批准号:
    9422255
  • 负责人:
  • 金额:
    $ 32万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    1996
  • 资助国家:
    美国
  • 起止时间:
    1996-10-01 至 1999-09-30
  • 项目状态:
    已结题

项目摘要

9422255 Kenny This GOALI proposal deals with the fabrication of high Q, single crystal, cantilevers for magnetic resonance force microscopy. These cantilevers are to be fabricated with microelectromechanical sensors (MEMS) technology at the Stanford NNUN facility. The PI plans to fabricate such cantilevers with the goal of improving the force detection sensitivity of a magnetic resonance force microscopy (MRFM) instrument to where atomic resolution may be possible. Through an increase of the quality factor, Q, from 106 to 108 and operation at low temperatures the PI expects to detect forces as low as 10-18 N/Hz1/2, which is several orders of magnitude more sensitive than present MRFM instruments. This would be a fundamental advance in the ability to detect small forces - in fact, the ability to detect magnetic forces from individual nuclear spins. Thus, this work would permit the realization of a micron-scale magnetometer with a ferromagnetic particle on the cantilever tip. The cantilever motion would be excited by the torsional coupling between the ferromagnetic particle's magnetic moment and an external oscillating magnetic field. One of the exciting possibilities of this research lies in the possibility of direct imaging of individual biological molecules (i.e. 'molecular' imaging) which aids in the determination of the molecular structure of molecules. STM and AFM techniques permit 2D "surface' imaging, but this technique could open the door to 3D imaging with the same resolution. The GOALI program will be a collaboration between Stanford and IBM Almaden who have demonstrated a prototype nuclear magnetic resonance (NMR) system. ***
这个GOALI提案涉及用于磁共振力显微镜的高Q单晶悬臂梁的制造。这些悬臂将在斯坦福大学NNUN工厂用微机电传感器(MEMS)技术制造。PI计划制造这样的悬臂梁,目的是提高磁共振力显微镜(MRFM)仪器的力检测灵敏度,使原子分辨率成为可能。通过将质量因子Q从106提高到108,并在低温下工作,PI预计可以检测到低至10-18 N/Hz1/2的力,这比目前的MRFM仪器灵敏几个数量级。这将是探测微小力的能力的一个根本性的进步——事实上,是探测单个核自旋产生的磁力的能力。因此,这项工作将允许实现在悬臂尖端具有铁磁颗粒的微米级磁力计。铁磁粒子的磁矩与外部振荡磁场之间的扭转耦合将激发悬臂运动。这项研究的一个令人兴奋的可能性在于个体生物分子的直接成像的可能性。“分子”成像)有助于确定分子的分子结构。STM和AFM技术允许二维“表面”成像,但这项技术可以为具有相同分辨率的三维成像打开大门。GOALI项目将由斯坦福大学和IBM阿尔马登公司合作进行,后者已经展示了一个核磁共振(NMR)系统的原型。* * *

项目成果

期刊论文数量(0)
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Thomas Kenny其他文献

Children's response to their true and distorted mirror images
Awareness of Fabry disease among non-Fabry specialists: Opportunities for education
非法布雷病专家对法布雷病的认识:教育的机会
  • DOI:
    10.1016/j.ymgme.2024.108796
  • 发表时间:
    2025-02-01
  • 期刊:
  • 影响因子:
    3.500
  • 作者:
    Thomas Kenny;Stuart Gaffney;Katy Bunn;Kamran Iqbal
  • 通讯作者:
    Kamran Iqbal
<strong>Audit of a global rare disease clinical trial support service</strong>
  • DOI:
    10.1016/j.ymgme.2019.11.013
  • 发表时间:
    2020-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Jacqueline M. Adam;Benedicta Marshall-Andrew;Thomas Kenny
  • 通讯作者:
    Thomas Kenny
98 Is primary biliary cirrhosis caused by molecular mimicry with novosphingobium aromaticivorans, a ubiquitous xenobiotic metabolizing bacterium?
98 原发性胆汁性肝硬化是由新鞘氨醇(一种普遍存在的异生物质代谢细菌)的分子模拟引起的吗?
  • DOI:
  • 发表时间:
    2003
  • 期刊:
  • 影响因子:
    0
  • 作者:
    C. Selmi;D. Balkwill;P. Invernizzi;A. Ansari;R. Coppel;M. Podda;P. Leung;Thomas Kenny;J. Vandewater;M. Kurth
  • 通讯作者:
    M. Kurth
<strong>Medical education needs to improve diagnosis of Fabry disease in the UK</strong>
  • DOI:
    10.1016/j.ymgme.2023.107833
  • 发表时间:
    2024-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Stuart Gaffney;Kamran Iqbal;Phil Dawson;Thomas Kenny
  • 通讯作者:
    Thomas Kenny

Thomas Kenny的其他文献

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{{ truncateString('Thomas Kenny', 18)}}的其他基金

Collaborative Research: Nonlinear Coupling and Relaxation Mechanisms in Micro-mechanics
合作研究:微观力学中的非线性耦合和弛豫机制
  • 批准号:
    1662464
  • 财政年份:
    2017
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant
Student Travel Support for Transducers 01, The 2001 International Conference on Solid-State Sensors and Actuators in Munich, Germany, June 10-14, 2001
传感器学生旅行支持 01,2001 年固态传感器和执行器国际会议,德国慕尼黑,2001 年 6 月 10-14 日
  • 批准号:
    0125062
  • 财政年份:
    2001
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant
GOALI: Advanced Cantilevers for MRFM with IBM Almaden
GOALI:采用 IBM Almaden 的 MRFM 高级悬臂梁
  • 批准号:
    9971414
  • 财政年份:
    1999
  • 资助金额:
    $ 32万
  • 项目类别:
    Continuing Grant
Microstructures for Experiments in Biology
生物学实验的微观结构
  • 批准号:
    9980838
  • 财政年份:
    1999
  • 资助金额:
    $ 32万
  • 项目类别:
    Continuing Grant
Student Travel Support to attend the 10th International Conference on Solid State Sensors and Actuators (Transducers '99) to be held in Sendai, Japan
学生旅行支持参加将于日本仙台举行的第十届固态传感器和执行器国际会议 (Transducers 99)
  • 批准号:
    9907883
  • 财政年份:
    1999
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant
Micromachined Calorimeter for Sep Diagnostics
用于 Sep 诊断的微机械量热仪
  • 批准号:
    9707181
  • 财政年份:
    1997
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant
Micromachined Calorimeter for SEP Diagnostics
用于 SEP 诊断的微机械热量计
  • 批准号:
    9612538
  • 财政年份:
    1996
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant
CAREER: Phonon Propagation in Confined Mechanical Geometries
职业:受限机械几何中的声子传播
  • 批准号:
    9502046
  • 财政年份:
    1995
  • 资助金额:
    $ 32万
  • 项目类别:
    Continuing Grant
Interferometer Instrumentation for Characterization of Micro-mechanical Structures
用于表征微机械结构的干涉仪仪器
  • 批准号:
    9504099
  • 财政年份:
    1995
  • 资助金额:
    $ 32万
  • 项目类别:
    Standard Grant

相似国自然基金

Research on the Rapid Growth Mechanism of KDP Crystal
  • 批准号:
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