The Johns Hopkins Protein Folding Meeting being held March 16-19, 1996 at the Coolfont Conference Center in Berkeley Springs, West Virginia

9513492拉特曼1996年约翰霍普金斯蛋白质折叠会议将于1996年3月16-19日在库尔方特会议中心举行，该中心距离巴尔的摩和华盛顿约2小时车程，位于西弗吉尼亚州伯克利斯普林斯。会议将包括4次三小时的演讲，由该领域的领导人计划和主持。其他活动包括第一次基督教安芬森讲座，海报会议，以及非正式交流的机会。会议材料将发表在《蛋白质：结构、功能和遗传学》杂志上。蛋白质折叠是指蛋白质分子呈现其正常功能形式的过程。在细胞中，蛋白质分子以灵活、延伸的链的形式制造--更像是一块煮熟的意大利面。然后，每条链自发地折叠成一个紧凑的球体，代表蛋白质分子的活性形式--所谓的自然状态。值得注意的事实是，特定蛋白质的所有分子都折叠成完全相同的自然状态。相比之下，如果将意大利面的每一条折叠起来，比如把它们放在勺子里，每一条意大利面都会以不同的方式折叠。蛋白质分子被称为链，因为它们是以一系列称为氨基酸的化学链的形式建立起来的。有20种不同的氨基酸类型。告诉蛋白质如何折叠的信息包含在蛋白质链中的氨基酸序列中。1996年约翰霍普金斯蛋白质折叠会议将汇聚来自世界各地的专家，介绍和讨论蛋白质折叠各个方面的新研究。主题将包括尝试预测蛋白质的天然结构，以及研究实际折叠过程的细节。请拨资金以支付演讲者和学生的出席费用。***

9513492 Lattman The 1996 Johns Hopkins Protein Folding Meeting will be held 16-19 March 1996 at the Coolfont Conference Center, located about 2 hours from Baltimore and Washington in Berkeley Springs West Virginia. The meeting will include 4 three-hour sessions of presented talks, planned and chaired by leaders in the field. Additional events include the first Christian Anfinsen Lecture, a poster session, and the opportunity for informal exchanges. Material from the meeting will be published in Proteins: Structure, Function and Genetics. %%% Protein folding is the name given to the process by which protein molecules assume their normal functional form. In cells protein molecules are manufactured in the form of flexibly, extended chains - rather like a microscopic piece of cooked spaghetti. Each strand then spontaneously folds up into a compact ball that represents the active form of the protein molecule - the so-called native state. The remarkable fact is that all the molecules of a particular protein fold up into exactly the same native state. In contrast, if one folds up individual strands of spaghetti, say by putting them in a spoon, each of the strands will fold up in a different way. Protein molecules are called chains because they are built up as a sequence of chemical links called amino acids. there are 20 different amino acid types. The information telling the protein how to fold up is contained in the sequence of the amino acids in the protein chain. The 1996 Johns Hopkins Protein Folding Meeting will gather together experts from all over the world to present and discuss new research on various aspects of protein folding. Topics will include attempts to predict the native structure of a protein, and studies on the details of the actual folding process. Funds are requested to defray the costs of attendance for speakers and students. ***