The Johns Hopkins Clinical Research Scholars in Women's Health (BIRCWH)

约翰霍普金斯大学女性健康临床研究学者 (BIRCWH)

• 批准号: 10683615
• 负责人: Daniel Ernest Ford
• 金额: $ 19.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683615
• 关键词: Administrative Supplement; Area; Attention; Cancer Biology; Cardiovascular system; Clinical; Clinical Research; Collaborations; Communities; Competence; Discipline; Discipline of Nursing; Disease; Faculty; Foundations; Funding; Genetic; Goals; Health; Immunology; Interdisciplinary Study; International; Lead; Life Cycle Stages; Mentors; Mentorship; Neurosciences; Outcome; Positioning Attribute; Poverty; Public Health; Reproductive Biology; Research; Research Personnel; Resources; Scientist; Secure; Sex Differences; Strategic Planning; Trauma; Underrepresented Minority; Underrepresented Populations; Woman; Women' s Health; addiction; base; black women; cardiometabolism; career; career development; cohort; experience; gender difference; health difference; health disparity; high risk population; improved; innovation; lens; medical schools; multidisciplinary; novel; programs; racial disparity; recruit; sex; social determinants; success; violence against women

PROJECT SUMMARY/ABSTRACT The overarching goal of the Johns Hopkins BIRCWH program (JH-BIRCWH) is to develop highly qualified, independent investigators who will conduct innovative and significant women’s health and sex and gender differences research. The program represents a successful and robust collaboration of the Johns Hopkins Schools of Medicine, Nursing, and Public Health. In our first period of support, we recruited 10 Scholars, all outstanding junior investigators from diverse disciplines, including 5 under-represented minorities. The success of the program is illustrated by their success: 100% (5/5) JH-BIRCWH alumni secured new external federal and/or foundation research funding. Because of JH-BIRCWH mentorship and career development, these Scholars continue to develop as independent investigators and leaders in innovative, interdisciplinary research. Scholars broaden their understanding through the lens of a life course perspective with particular attention to research on the health needs of diverse and high-risk populations. During this next proposed period of support, our JH-BIRCWH program is well positioned for sustained success. Consistent with the Office of Research on Women’s Health (ORWH) strategic plan (2019-2023), we will continue to recruit highly motivated junior faculty scholars, with priority given to investigators from groups underrepresented in research. We will build on the established foundation of our learner-centered and competency-based approach to interdisciplinary career development. A critical resource for the JH-BIRCWH program is the cadre of highly experienced, internationally recognized faculty who are active in research related to women’s health or sex/gender differences, and who are committed to supporting and sponsoring Scholars. The three core strength areas of the JH-BIRCWH program are: 1) diseases specific to women (e.g. women’s cancer and reproductive biology); 2) sex and gender differences in disease expression (e.g. immunology, neuroscience, cardiovascular and genetics); and 3) social determinants of women’s health and disparities (e.g. violence against women, trauma, addictions and poverty). During this administrative supplement, the JH-BIRCWH will annually support 1 scholar. This scholar will receive expert mentoring from a multidisciplinary team along with funding, and access to institutional resources that are also available to our current cohort of BIRCWH scholars. The scholar’s long-term goal is to establish a career as a clinician-scientist and independent investigator focused on identifying novel clinical and community-based strategies to eliminate racial disparities in maternal cardiometabolic outcomes among Black women. With the support of this supplemental funding, they will be well prepared to lead interdisciplinary teams to improve women’s health by advancing their understanding of sex gender differences and health concerns unique to, more prevalent, or with differential consequences in women.

项目概要/摘要 约翰·霍普金斯大学 BIRCWH 计划 (JH-BIRCWH) 的总体目标是培养高素质、 独立调查人员将开展创新且重要的妇女健康、性和性别研究 差异研究。该计划代表了约翰霍普金斯大学的成功和强有力的合作 医学院、护理学院和公共卫生学院。在我们的第一期支持中，我们招募了 10 名学者，全部 来自不同学科的杰出初级研究者，其中包括 5 个代表性不足的少数群体。成功 该计划的成功体现在：100% (5/5) JH-BIRCWH 校友获得了新的外部联邦资助 和/或基金会研究经费。由于 JH-BIRCWH 的指导和职业发展，这些 学者们继续发展成为创新、跨学科研究的独立研究者和领导者。 学者们通过生命历程的视角拓宽了他们的理解，特别关注 研究多样化和高风险人群的健康需求。在下一个提议的支持期内， 我们的 JH-BIRCWH 计划已做好了持续成功的准备。与研究办公室一致 妇女健康（ORWH）战略计划（2019-2023），我们将继续招募积极性高的初级教师 学者，优先考虑来自研究中代表性不足的群体的研究人员。我们将在此基础上 为我们以学习者为中心、以能力为基础的跨学科职业方法奠定了基础 发展。 JH-BIRCWH 计划的一个重要资源是经验丰富的国际化骨干队伍 积极从事与女性健康或性/性别差异相关研究的公认教师，并且 致力于支持和资助学者。 JH-BIRCWH项目的三大核心优势领域 是： 1) 女性特有的疾病（例如女性癌症和生殖生物学）； 2）性别和性别 疾病表达的差异（例如免疫学、神经科学、心血管和遗传学）； 3）社会 妇女健康和差异的决定因素（例如暴力侵害妇女行为、创伤、毒瘾和贫困）。 在此行政补充期间，JH-BIRCWH 将每年资助 1 名学者。这位学者将获得 来自多学科团队的专家指导以及资金和获得机构资源的机会 也可供我们目前的 BIRCWH 学者群体使用。学者的长远目标是建立事业 作为一名临床医生科学家和独立研究者，专注于识别新颖的临床和基于社区的 消除黑人妇女孕产妇心脏代谢结果的种族差异的策略。随着 在这笔补充资金的支持下，他们将做好充分准备，带领跨学科团队改进 通过增进她们对性别差异和独特的健康问题的理解来促进妇女的健康， 在女性中更为普遍，或产生不同的后果。

项目成果

The Use of Echocardiography and Advanced Cardiac Ultrasonography During Pregnancy.

• DOI: 10.1007/s11936-019-0785-5
• 发表时间: 2019-11-21
• 期刊: Current treatment options in cardiovascular medicine
• 作者: O'Kelly AC;Sharma G;Vaught AJ;Zakaria S
• 通讯作者: Zakaria S

Antibodies against Angiotensin II Type 1 and Endothelin A Receptors: Relevance and pathogenicity.

• DOI: 10.1016/j.humimm.2019.04.012
• 发表时间: 2019-08
• 期刊: Human immunology
• 影响因子: 2.7
• 作者: Philogene MC;Johnson T;Vaught AJ;Zakaria S;Fedarko N
• 通讯作者: Fedarko N

Sexual and Reproductive Health and Reproductive Coercion in Women Victim/Survivors Receiving Housing Support.

接受住房支持的女性/幸存者的性健康和生殖健康和生殖胁迫。

• DOI: 10.1007/s10896-022-00362-0
• 发表时间: 2023
• 期刊: Journal of family violence
• 影响因子: 3.8
• 作者: Grace KT;Holliday CN;Bevilacqua K;Kaur A;Miller J;Decker MR
• 通讯作者: Decker MR

Maternal sepsis.

产妇败血症。

• DOI: 10.1053/j.semperi.2017.11.003
• 发表时间: 2018
• 期刊: Seminars in perinatology
• 影响因子: 3.4
• 作者: Vaught,ArthurJason

Mental health, chronic and infectious conditions among pregnant persons in US state prisons and local jails 2016-2017.

2016-2017 年美国州立监狱和地方监狱孕妇的心理健康、慢性和传染病状况。

• DOI: 10.1177/17455057241228748
• 发表时间: 2024
• 期刊: Women's health (London, England)
• 作者: Hendricks,CaitlinA;Rajagopal,KarissaM;Sufrin,CarolynB;Kramer,Camille;Jiménez,MonikC
• 通讯作者: Jiménez,MonikC