RIMI: RPG: Molecular and Biochemical Studies of Surface Proteins and Cell Signalling

RIMI：RPG：表面蛋白和细胞信号传导的分子和生化研究

• 批准号: 9550643
• 负责人: Etheleen McGinnis
• 金额: $ 4.98万
• 依托单位: Meharry Medical College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-09-01 至 1997-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9550643&HistoricalAwards=false
• 关键词: RIMI; RPG; Molecular; Biochemical; Studies

9550643 Hill Planning activities related to the investigation of Bartonella bacilliformis receptors and signaling mechanisms are proposed. Specific aims of the planning activities include (1) performance of preliminary investigations on Bartonella bacilliformis (2) collaborations with Dr. Hoover (at Vanderbilt) and Dr. Minnick (at the University of Montana) and (3) attend several scientific meetings. The specific aims of the research are (1) identify and characterize the Bartonella receptor on host cell surfaces (2) determine whether protein phosphorylation has a role in the uptake of Bartonella into host cells (3) determine whether outer membrane proteins of Bartonella can stimulate host target cells to proliferate. ***

小行星9550643 规划活动有关的调查巴尔通体bacilliformis受体和信号传导机制的建议。 计划活动的具体目标包括：（1）对杆菌形巴尔通体进行初步调查;（2）与胡佛博士（在范德比尔特）和明尼克博士（在蒙大拿大学）合作;（3）参加几次科学会议。 本研究的具体目的是（1）鉴定和表征宿主细胞表面的巴尔通体受体（2）确定蛋白磷酸化是否在巴尔通体被宿主细胞摄取中起作用（3）确定巴尔通体外膜蛋白是否能够刺激宿主靶细胞增殖。 ***