High Resolution SQUID Magnetometer for Imaging Biological Systems

用于生物成像系统的高分辨率 SQUID 磁力计

• 批准号: 9604948
• 负责人: John Wikswo
• 金额: $ 29.9万
• 依托单位: Vanderbilt University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2000-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9604948&HistoricalAwards=false
• 关键词: Resolution; SQUID; Magnetometer; Imaging; Biological

The objective of the proposed research is to continue to develop ultra-high resolution, Superconducting Quantum Interference Device (SQUID) magnetometers (UHRSM) that are optimized for the imaging of the magnetic fields produced by action currents, remanent magnetization, and magnetic susceptibility in isolated living tissue and small experimental animal preparations at the scale of 100 m. Such measurements are not yet in wide spread use, primarily because of the limitations and costs of existing instrumentation. This project is designed specifically to address these points. The proposed instruments will be capable of making measurements that are impossible with any other technique, and should lead to new insights into cellular biology, electrophysiology, botany, embryology, magnetoreception, immunodiagnostics, and neurophysiology.

这项拟议研究的目标是继续开发超高分辨率超导量子干涉器件(SQUID)磁强计(UHRSM)，该磁强计针对100米尺度的隔离活组织和小型实验动物标本中的作用电流、剩余磁化和磁化率产生的磁场进行成像优化。这种测量尚未广泛使用，主要是因为现有仪器的限制和成本。这个项目就是专门为解决这些问题而设计的。拟议中的仪器将能够进行任何其他技术无法进行的测量，并将导致对细胞生物学、电生理学、植物学、胚胎学、磁接收、免疫诊断学和神经生理学的新见解。