CRB: Molecular Identification of Threatened Species: Does Theory Predict the Utility of Nuclear vs. Mitochondrial Sequences?
CRB:受威胁物种的分子鉴定:理论是否预测核序列与线粒体序列的效用?
基本信息
- 批准号:9622182
- 负责人:
- 金额:$ 11万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:1996
- 资助国家:美国
- 起止时间:1996-06-01 至 1998-05-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
9622182 Palumbi Most species are comprised on interacting populations, and describing these interactions are understanding their consequences remains one of the greatest challenges in conservation biology. To date, metapopulation modeling and demographic description of interacting populations have been matched by technical advances in the detection of genetic differences within and between populations. However, a comprehensive melding of demographic, modeling and genetic approaches to metapopulations has yet to be achieved. When is an ecological population identifiable as a genetic population? When do differences in genetics correctly predict results of metapopulation models? These questions need to be answered to bring genetic and ecological approaches to metapopulations together. This research seeks to understand the processes by which populations become genetically distinct from one another. Such genetic distinctions are at the heart of recent definitions of evolutionarily significant units for conservation management which depend on reciprocal monophyly of populations at some genetic locus. Previously, much attention has been placed on mitochondrial DNA because these loci become monophyletic rapidly. However, mtDNA can not be used to parameterize ecological models of population structure because mtDNA only tracks maternal inheritance patterns. How useful are nuclear loci in discriminating populations genetically? This depends on the rate of development of monophyly of nuclear genes compared to mitochondrial genes. Population genetic theory predicts a simple relationship between these two rates, but this prediction depends on many assumptions that have never been tested in any animal system. This conservation biology research will investigate the development of reciprocal monophyly in mitochondrial and nuclear loci in a set of defined species of whales and dolphins. This study will have direct application to the rate at which populations become distinguishable genetically and ecologically . This is a central questions when dealing with populations of endangered species. In addition, the genetic markers developed in this research will have important practical applications for monitoring whale and dolphin populations.
大多数物种是由相互作用的种群组成的,描述这些相互作用是了解它们的后果,这仍然是保护生物学中最大的挑战之一。迄今为止,在检测种群内部和种群之间的遗传差异方面的技术进步与元种群模型和相互作用种群的人口统计学描述相匹配。然而,人口统计学、建模和遗传方法对元人口的全面融合尚未实现。什么时候一个生态种群可以被识别为一个遗传种群?什么时候基因差异能正确预测元种群模型的结果?这些问题需要得到回答,以便将遗传和生态方法结合起来研究超种群。这项研究旨在了解人群在基因上彼此不同的过程。这种遗传差异是最近对保护管理的进化重要单位的定义的核心,这种定义依赖于某些遗传位点上种群的相互单系性。在此之前,人们对线粒体DNA的关注很大,因为这些基因座很快就会变成单系的。然而,由于mtDNA仅追踪母体遗传模式,因此不能用于参数化种群结构的生态模型。核位点在基因上区分种群有多有用?这取决于与线粒体基因相比,核基因单一性的发展速度。种群遗传理论预测了这两种比率之间的简单关系,但这种预测依赖于许多从未在任何动物系统中验证过的假设。这项保护生物学研究将调查一系列鲸鱼和海豚物种中线粒体和核位点的互惠单系性的发展。这项研究将直接应用于种群在遗传和生态上变得可区分的速度。这是处理濒危物种种群时的一个核心问题。此外,本研究开发的遗传标记将在监测鲸鱼和海豚种群方面具有重要的实际应用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Stephen Palumbi其他文献
Stephen Palumbi的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Stephen Palumbi', 18)}}的其他基金
Predicting the global location of heat tolerant corals: Palau patch reefs as a general model
预测耐热珊瑚的全球位置:帕劳斑块珊瑚礁作为通用模型
- 批准号:
1736736 - 财政年份:2017
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
RAPID: Ecological, evolutionary and physiological responses of corals to a mass bleaching event in American Samoa
快速:珊瑚对美属萨摩亚大规模白化事件的生态、进化和生理反应
- 批准号:
1547921 - 财政年份:2015
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
High resolution genome changes during evolution in a classic fisheries experiment
经典渔业实验中进化过程中的高分辨率基因组变化
- 批准号:
1434325 - 财政年份:2014
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Understanding thermal adaptation to climate change using a globally invasive species
论文研究:利用全球入侵物种了解对气候变化的热适应
- 批准号:
1210057 - 财政年份:2012
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
OCEAN ACIDIFICATION - Category 1: COLLABORATIVE RESEARCH: Acclimation and adaptation to ocean acidification of key ecosystem components in the California Current System
海洋酸化 - 第 1 类:合作研究:加州洋流系统关键生态系统组成部分对海洋酸化的适应和适应
- 批准号:
1041222 - 财政年份:2010
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
SGER: Population variation and environmental adaptation in all the genes of the purple sea urchin
SGER:紫海胆所有基因的种群变异和环境适应
- 批准号:
0714997 - 财政年份:2007
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
Identity and Characterization of Genes Fundamental in Speciation
物种形成基础基因的身份和表征
- 批准号:
0318637 - 财政年份:2002
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
Identity and Characterization of Genes Fundamental in Speciation
物种形成基础基因的身份和表征
- 批准号:
0089681 - 财政年份:2001
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
Dissertation Research: The Effects of Ecological Constraints on Polygyny in Argentine Ants
论文研究:生态约束对阿根廷蚂蚁一夫多妻制的影响
- 批准号:
9972725 - 财政年份:1999
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
An Experimental Study of the Role of Gamete Recognition in Reproductive Isolation
配子识别在生殖隔离中作用的实验研究
- 批准号:
9707220 - 财政年份:1997
- 资助金额:
$ 11万 - 项目类别:
Standard Grant
相似国自然基金
Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
- 批准号:81300605
- 批准年份:2013
- 资助金额:23.0 万元
- 项目类别:青年科学基金项目
Molecular Plant
- 批准号:31224801
- 批准年份:2012
- 资助金额:20.0 万元
- 项目类别:专项基金项目
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
- 批准号:31070748
- 批准年份:2010
- 资助金额:34.0 万元
- 项目类别:面上项目
Molecular Plant
- 批准号:31024802
- 批准年份:2010
- 资助金额:20.0 万元
- 项目类别:专项基金项目
Cellular & Molecular Immunology
- 批准号:30824806
- 批准年份:2008
- 资助金额:20.0 万元
- 项目类别:专项基金项目
相似海外基金
Identification a novel bone-generating macrophage subset and their molecular mechanisms.
鉴定一种新型的骨生成巨噬细胞亚群及其分子机制。
- 批准号:
24K19848 - 财政年份:2024
- 资助金额:
$ 11万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
AIPPN: Interpretable AI enabled Molecular Identification Pipeline for Plant-parasitic Nematodes
AIPPN:可解释的人工智能支持植物寄生线虫分子识别管道
- 批准号:
10077647 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Collaborative R&D
Identification of Genetic and Molecular Bases of Derived Phenotypes in Primate Brain Development
灵长类动物大脑发育中衍生表型的遗传和分子基础的鉴定
- 批准号:
10841947 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Identification of the molecular and cellular mechanisms driving cardiac fibrosis: A novel ex-vivo approach to target identification and validation
驱动心脏纤维化的分子和细胞机制的鉴定:一种新颖的体外靶标鉴定和验证方法
- 批准号:
NC/X001733/1 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Training Grant
Identification of the molecular genetic bases for evolution to trioecious green alga through whole genome analysis
通过全基因组分析鉴定绿藻三异株进化的分子遗传基础
- 批准号:
23K19345 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Grant-in-Aid for Research Activity Start-up
Identification of factor driving underwater photosynthesis and its molecular evolution
水下光合作用驱动因素识别及其分子进化
- 批准号:
22KJ2792 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Grant-in-Aid for JSPS Fellows
Identification of the molecular regulation between cell survival and cell death in response to infection induced inflammasome activation.
识别响应感染诱导的炎症小体激活的细胞存活和细胞死亡之间的分子调节。
- 批准号:
10782349 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Identification and characterization of molecular subtypes of Alzheimer's disease associated with cognitive function through cross-omics data integration
通过跨组学数据整合识别和表征与认知功能相关的阿尔茨海默病分子亚型
- 批准号:
10722083 - 财政年份:2023
- 资助金额:
$ 11万 - 项目类别:
Molecular identification of the oxygen sensor(s) in the fetal ductus arteriosus and pulmonary artery: an integrated multiomic comparison of mitochondria in vital fetal arteries with opposing oxygen responses
胎儿动脉导管和肺动脉中氧传感器的分子识别:对胎儿重要动脉中具有相反氧反应的线粒体进行综合多组学比较
- 批准号:
462691 - 财政年份:2022
- 资助金额:
$ 11万 - 项目类别:
Operating Grants
Identification of macrotranscytosis based on clarification of the molecular mechanism of transport of tissue barrier penetrating peptides
基于阐明组织屏障穿透肽转运分子机制的大转胞吞作用的鉴定
- 批准号:
22H02786 - 财政年份:2022
- 资助金额:
$ 11万 - 项目类别:
Grant-in-Aid for Scientific Research (B)