FT-NMR Spectrometer

傅里叶变换核磁共振波谱仪

• 批准号: 9650217
• 负责人: Allen Schoffstall
• 金额: $ 6.25万
• 依托单位: University of Colorado at Colorado Springs
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9650217&HistoricalAwards=false
• 关键词: FT; NMR; Spectrometer

This department is obtaining instrumentation suitable to determine high-field lH and 13C Fourier-transform nuclear magnetic resonance (FT-NMR) spectra in an undergraduate environment, which includes classroom work and undergraduate research. The 200-MHz instrument has excellent sensitivity and resolution capabilities at a reasonable cost. The software used is similar to that of other sophisticated instruments, so that students going elsewhere after graduation will be able to adjust to the operation of FT-NMR equipment at a new location. Spectra are to be obtained directly by students, the new equipment being amenable to such a policy. Each student-user experiences proving the structure of unknowns using lH and 13C FT-NMR, verifying the structure of a product of reaction, measuring the percentage of components in an equilibrium or a mixture, deriving structural information from both lH and 13C FT-NMR, analyzing patterns of coupling through decoupling techniques, measuring relaxation times, noting effects in variable-temperature spectra, and analyzing other problems. Students also see how FT-NMR spectra can be used in tandem with other analytical methods, such as gas and liquid chromatography, and with other spectroscopic methods, such as infrared ultraviolet-visible spectroscopy and mass spectrometry, to solve structural and analytical problems. Through direct participation in operating the FT-NMR spectrometer and interpreting results, students gain hands-on experience with a method of structural analysis that has become crucial to the progress and development of chemical knowledge. This is important for students who are new to chemistry and also for those who are engaged in undergraduate research projects.

该部门正在获得适合在本科环境中确定高场1H和13 C傅里叶变换核磁共振（FT-NMR）光谱的仪器，其中包括课堂工作和本科研究。200 MHz仪器具有出色的灵敏度和分辨率能力，成本合理。所使用的软件与其他复杂仪器的软件相似，因此毕业后前往其他地方的学生将能够在新的地点调整FT-NMR设备的操作。光谱将由学生直接获得，新设备符合这样的政策。每个学生用户体验使用1H和13 C FT-NMR证明未知物的结构，验证反应产物的结构，测量平衡或混合物中组分的百分比，从1H和13 C FT-NMR导出结构信息，通过解耦技术分析耦合模式，测量弛豫时间，注意变温光谱中的影响，以及分析其他问题。学生还将了解FT-NMR光谱如何与其他分析方法（如气相色谱法和液相色谱法）以及其他光谱方法（如红外紫外可见光谱法和质谱法）一起使用，以解决结构和分析问题。 通过直接参与操作FT-NMR光谱仪和解释结果，学生可以获得结构分析方法的实践经验，这种方法对化学知识的进步和发展至关重要。这对于化学新手和从事本科研究项目的学生来说非常重要。