Integration of Multinuclear FT-NMR into the Chemistry Curriculum

将多核 FT-NMR 纳入化学课程

• 批准号: 9750684
• 负责人: Gary Breton
• 金额: $ 2.11万
• 依托单位: Berry College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9750684&HistoricalAwards=false
• 关键词: Integration; Multinuclear; FT; NMR; into

Fourier-transform nuclear magnetic resonance (FT-NMR) spectroscopy is a powerful, state-of-the-art analytical method used commonly in industrial and graduate school settings. This project integrates modern FT-NMR concepts more firmly into the chemistry curriculum. An upgrade of an outdated, continuous-wave 60-MHz instrument to an FT system allows full implementation of the project. This upgrade dramatically increases the utility of magnets without introducing the high maintenance and purchasing costs associated with a superconducting NMR magnet. The upgraded system provides the capability to (1) provide hands-on NMR experience as early as the sophomore year, (2) introduce 13C NMR spectroscopy, (3) perform new laboratory experiments (e.g., experiments in kinetics and characterization of reactive intermediates), (4) investigate advanced NMR topics (such as FID collection, two-dimensional spectra, relaxation times, and signal-averaging) and (5) perform a host of other new applications. Specific improvements in five laboratory-based chemistry courses begin with sophomore-level organic chemistry and continue through senior-level advanced courses. Students graduate with extensive first-hand experience on an FT-NMR instrument, a thorough knowledge of the principles behind NMR, and confidence in spectral interpretation. A comprehensive evaluation plan has been forged which relies on assessment of student performance on laboratory reports, course exams, and nationally standardized NMR-related test questions. *

傅里叶变换核磁共振（FT-NMR）光谱是一种强大的、最先进的分析方法，通常用于工业和研究生院的设置。该项目将现代FT-NMR概念更牢固地融入化学课程。将过时的60 mhz连续波仪器升级为FT系统，可以全面实施该项目。这种升级极大地提高了磁铁的效用，而不引入与超导核磁共振磁铁相关的高维护和购买成本。升级后的系统提供了以下能力：(1)早在大二就提供实际的核磁共振经验，(2)介绍13C核磁共振波谱，(3)进行新的实验室实验（例如，动力学实验和反应中间体的表征），(4)研究高级核磁共振主题（例如FID收集，二维光谱，松弛时间和信号平均）以及(5)执行许多其他新应用程序。五门以实验为基础的化学课程，从二年级的有机化学课程开始，持续到高年级的高级课程。学生毕业时对FT-NMR仪器有广泛的第一手经验，对NMR背后的原理有透彻的了解，对光谱解释有信心。通过实验室报告、课程考试和国家核磁共振标准化试题对学生的表现进行评估，形成了一套综合评估方案。＊