NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

摘要DBI-9803904马克·L·西格尔这一行动为美国国家科学基金会/阿尔弗雷德·P·斯隆1998年分子进化博士后研究奖学金提供了资金。这些奖学金支持在有机体进化变化和适应的框架内，在分子水平上对生物模式和过程进行理论、比较、计算和/或实验分析的研究。这些研究还包括使用分子数据来解决更广泛的进化问题。每个研究金资助一项研究和培训计划，该计划将在一个赞助实验室进行。这项研究和培训计划的题目是昆虫性别决定途径的分子进化。果蝇的性别决定是发育过程中遗传等级的模型。众所周知的各种主要性别决定机制表明，性别决定是非常可塑性的，在进化过程中经常发生变化。参考果蝇的详细知识，正在采取比较的方法来探索昆虫遗传性别决定的不同模式。

Abstract DBI-9803904 Mark L. Siegal This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary change and adaptation. These studies also include the use of molecular data to address broader evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled molecular evolution of the sex-determination pathway in insects. Sex determination in Drosophila is a model for genetic hierarchies in development. The well-known variety of primary sex-determining mechanisms suggests that sex determination is exceptionally plastic, changing often in evolution. A comparative approach is being taken to probe the divergent modes of genetic sex determination in insects, with reference to the detailed knowledge from Drosophila.