NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

NSF/Alfred P. Sloan 基金会 1998 财年分子进化博士后研究奖学金

• 批准号: 9803949
• 负责人: Bonnie McCaig
• 金额: $ 8万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-01 至 2000-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9803949&HistoricalAwards=false
• 关键词: NSF; Alfred; P.; Sloan; Foundation

Abstract DBI-9803949 Bonnie C. McCaig This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary change and adaptation. These studies also include the use of molecular data to address broader evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled evolution of structural components of plants. The lignin in conifers arises from the polymerization of one precursor, whereas that in flowering plants arises from two. The question being addressed is did a second laccase gene family coincide with the origin of syringyl lignin in angiosperms? The two classes of lignin-polymerizing laccases have different substrate preferences, and these classes may be expressed differentially during plant development. This project examines the molecular evolution of genes encoding laccases, the enzymes catalyzing lignin polymerization, to determine whether a separate biosynthetic pathway evolved to supply the syringyl component of angiosperm lignin. Gene phylogenies and expression studies are used to determine whether the classes diverged in parallel with changes in lignin and cell composition during plant evolution.

摘要DBI-9803949 Bonnie C.麦凯格 这一行动为1998年NSF/Alfred P. Sloan分子进化博士后研究奖学金提供资金。 这些奖学金支持研究涉及的理论，比较，计算，和/或实验分析的生物模式和过程在分子水平的框架内器官的进化变化和适应。这些研究还包括使用分子数据来解决更广泛的进化问题。 每项研究金资助一项研究和培训计划，该计划将在一个赞助实验室进行。 该奖学金的研究和培训计划题为植物结构成分的进化。针叶树中的木质素来自一种前体的聚合，而开花植物中的木质素来自两种前体。目前的问题是，第二个漆酶基因家族是否与被子植物中木质素的起源相一致？这两类木质素聚合漆酶具有不同的底物偏好性，并且这些类别在植物发育过程中可能差异表达。该项目研究了编码漆酶（催化木质素聚合的酶）的基因的分子进化，以确定是否进化出一条单独的生物合成途径来提供被子植物木质素中的辛烯基组分。基因的遗传和表达的研究，以确定是否在植物进化过程中的木质素和细胞组成的变化平行的类分歧。