NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

NSF/Alfred P. Sloan 基金会 1998 财年分子进化博士后研究奖学金

• 批准号: 9803938
• 负责人: Dawn Field
• 金额: $ 8万
• 依托单位: Fellowships
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-01 至 2000-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9803938&HistoricalAwards=false
• 关键词: NSF; Alfred; P.; Sloan; Foundation

Abstract DBI-9803938 Dawn Field This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary change and adaptation. These studies also include the use of molecular data to address broader evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled adaptive molecular evolution of a bacterial pathogen. Thirteen mutable repeats (microsatellites) are embedded within virulence factors in Haemophilus. influenzae. This study tests the hypothesis that genetic variability at these repeats is an important factor in determining the evolutionary success of individual isolates of this bacterium. One hundred twenty epidemiologically diverse strains of H. influenzae are being genotyped, and rates of mutation determined.

摘要 DBI-9803938 Dawn Field 这一行动为1998年NSF/Alfred P. Sloan分子进化博士后研究奖学金提供资金。 这些奖学金支持研究涉及的理论，比较，计算，和/或实验分析的生物模式和过程在分子水平的框架内器官的进化变化和适应。 这些研究还包括使用分子数据来解决更广泛的进化问题。 每项研究金资助一项研究和培训计划，该计划将在一个赞助实验室进行。 该奖学金的研究和培训计划题为细菌病原体的适应性分子进化。 嗜血杆菌的毒力因子中含有13个可变重复序列（微卫星）。流感。这项研究测试的假设，在这些重复的遗传变异是一个重要的因素，在确定这种细菌的个别菌株的进化成功。 120株流行病学上不同的H.正在对流感进行基因分型，并确定突变率。