NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

Amy L. Denton此行动资助了1998年NSF/Alfred P. Sloan分子进化博士后研究奖学金。这些奖学金支持涉及生物进化问题框架内分子水平生物模式和过程的理论、比较、计算和/或实验分析的研究。每个奖学金支持在赞助实验室进行的研究和培训计划。该奖学金的研究和培训计划题为“两种草的查尔酮合成酶基因的自然选择和其他进化过程的历史”。本研究利用聚结理论研究了玉米和珍珠粟查尔酮合成酶（Chs）位点的进化。通过对Chs基因系谱的统计分析，评价了有效群体大小、突变、重组和选择的相对重要性。该研究的主要目标是检测选择的影响，并探索在主要植物生物合成途径中控制分子多样性的历史力量。

Abstract DBI-9803908 Amy L. Denton This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled the history of natural selection and other evolutionary processes in the chalcone synthase genes of two grass species. This study uses coalescent theory to examine evolution at the chalcone synthase (Chs) loci in maize and pearl millet. The relative importance of effective population size, mutation, recombination and selection is being evaluated through statistical analyses of Chs gene genealogies. The primary goal of the research is to detect the influence of selection and explore the historical forces that have governed molecular diversity in a major plant biosynthetic pathway.