NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

DBI-9803929埃里克·舒尔特斯这一行动为美国国家科学基金会/阿尔弗雷德·P·斯隆1998年分子进化博士后研究奖学金提供了资金。这些奖学金支持在有机体进化变化和适应的框架内，在分子水平上对生物模式和过程进行理论、比较、计算和/或实验分析的研究。这些研究还包括使用分子数据来解决更广泛的进化问题。每个研究金资助一项研究和培训计划，该计划将在一个赞助实验室进行。该研究金的研究和培训计划名为测量自然选择对RNA结构的影响。除了进化修饰强加的结构特性外，进化的RNA还显示出RNA聚合物折叠所固有的特性。进化和随机序列的结构特性正在被比较，以提供对进化修改RNA序列和结构的机制的洞察。这些研究将开始解决RNA进化的历史特征，这些特征与RNA聚合物折叠所固有的特征是一致的。

Abstract DBI-9803929 Erik Schultes This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary change and adaptation. These studies also include the use of molecular data to address broader evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled measuring the effects of natural selection on RNA structure. In addition to structural properties imposed by evolutionary modification, evolved RNAs also display properties intrinsic to RNA polymer folding. The structural properties of evolved and random sequences are being compared to provide insight into the mechanisms by which evolution modifies RNA sequence and structure. These studies will begin to resolve features of RNA evolution that are historically contingent from those that are inherent to RNA polymer folding.