Fourth International Workshop on Chromosome Segregation and Aneuploidy to be held July 1-6, 1998 in Porto, Portugal

第四届染色体分离和非整倍性国际研讨会将于1998年7月1日至6日在葡萄牙波尔图举行

• 批准号: 9811587
• 负责人: Barbara Hamkalo
• 金额: $ 0.5万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-15 至 1999-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9811587&HistoricalAwards=false
• 关键词: Fourth; International; Workshop; Chromosome; Segregation

Hamkalo9811587Faithful partition of genetic information during mitosis and meiosis is the result of an ordered series of events culminating in the attachment of chromosomes to the spindle via a properly functioning centromere, chromosome disjunction and movement of chromatids or homologs to opposite poles of a functional spindle. A defect in any of these processes will result in aberrant chromosome segregation and, ultimately, aneuploidy. A thorough understanding of these processes will require information from simple, genetically tractable systems such as budding and fission yeasts, as well as work on metazoans. Progress can be facilitated by sustained communication and interaction among individuals studying different aspects of the process in different systems. The objectives of this conference, "Fourth International Workshop on Chromosome Segregation and Aneuploidy" which will be held in Porto, Portugal, July 1-6, 1998 are to foster the exchange of information and to bring together research scientists from around the world who are studying different aspects of chromosome structure, dynamics and segregation at the molecular, genetic, and cellular levels.

Hamkalo9811587在有丝分裂和减数分裂期间遗传信息的忠实分配是一系列有序事件的结果，这些事件最终通过正常功能的着丝粒、染色体分离和染色单体或同源物向功能性纺锤体的相反两极的移动而将染色体附着到纺锤体上。这些过程中的任何一个缺陷都会导致异常的染色体分离，最终导致非整倍性。要彻底了解这些过程，需要从简单的、遗传上易于处理的系统（如出芽和裂变酵母）以及后生动物的工作中获得信息。 在不同系统中研究这一进程不同方面的个人之间的持续交流和互动可促进取得进展。将于1998年7月1日至6日在葡萄牙波尔图举行的“第四届染色体分离和非整倍性国际研讨会”的目的是促进信息交流，并使来自世界各地在分子、遗传和细胞水平上研究染色体结构、动力学和分离的不同方面的研究科学家聚集在一起。